ArticleMagma (New York, N.Y.)2022
Investigating acute changes in osteoarthritic cartilage by integrating biomechanics and statistical shape models of bone: data from the osteoarthritis initiative.
Article in Magma (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Sex-Specific Adolescent Development of the Trochlea and Distal Femoral Physis: A 3D Shape Modeling Study.Orthopaedic journal of sports medicine · 2026Article
- Perspective: One and one make three - leveraging the synergy of imaging and biomechanics in osteoarthritis research and care.Osteoarthritis imaging · 2026Article
- Measures of resting cartilage structure and composition in runners with and without knee osteoarthritis.Osteoarthritis and cartilage open · 2026Article
- BMI and Varus Malalignment Compound to Define a High-Risk Phenotype for Compartment-Specific Knee Osteoarthritis Progression.medRxiv : the preprint server for health sciences · 2026Article
- Investigation of Anatomical and Morphological Variations in the Femur of a Chinese Population Using Statistical Shape Model.Orthopaedic surgery · 2026Article
- 3D Patellar instability Anatomical Severity Score (3D-PASS): A Novel Machine Learning Score Using 3D Bone Position From MRI to Predict Outcomes of Patellar Instability Treatment (Using a Subset of Data in the JUPITER Cohort).Orthopaedic journal of sports medicine · 2025Article
- Exercise-Induced Changes in Knee Cartilage In Vivo: Comparing MRI Sequences.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Improving Accuracy and Reproducibility of Cartilage TJournal of magnetic resonance imaging : JMRI · 2025Article
- ShapeMed-Knee: A Dataset and Neural Shape Model Benchmark for Modeling 3D Femurs.IEEE transactions on medical imaging · 2025Article
- ShapeMed-Knee: A Dataset and Neural Shape Model Benchmark for Modeling 3D Femurs.medRxiv : the preprint server for health sciences · 2024Article
- Compositional MR imaging of cartilage and joint mechanics.Osteoarthritis imaging · 2024Article
- Imaging of joint response to exercise with MRI and PET.Skeletal radiology · 2023Review
- A Correspondence-Based Network Approach for Groupwise Analysis of Patient-Specific Spatiotemporal Data.Annals of biomedical engineering · 2023Article
- Morphological and mechanical alterations in articular cartilage and subchondral bone during spontaneous hip osteoarthritis in guinea pigs.Frontiers in bioengineering and biotechnology · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveThis proof-of-principle study integrates joint reaction forces (JRFs) and bone shape to assess acute cartilage changes from walking and cycling.
methodsSixteen women with symptomatic knee osteoarthritis were recruited. Biomechanical assessment estimated JRFs during walking and cycling. Subsamples had magnetic resonance imaging (MRI) performed before and after a 25-min walking (n = 7) and/or cycling (n = 9) activity. MRI scans were obtained to assess cartilage shape and composition (T
resultsCartilage thickness (interior lateral, Δ - 0.10 mm) and T DISCUSSION: Walking and cycling caused distinct patterns of cartilage deformation, which depended on knee JRFs and bone morphology. For the first time, these results show that cartilage deformation is dependent on bone shapes and JRFs in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.