Evidence map›Paper›PMID 35286700›Full record

ReviewAdvances in experimental medicine and biology2022

The Immunogenetics of Vasculitis.

Fotini B Karassa, Eleftherios Pelechas, Georgios Zouzos

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fotini B KarassaDivision of Rheumatology, Department of Medicine, School of Health Sciences, University of Ioannina, 45110, Ioannina, Greece. fkarassa@uoi.gr.ORCID https://orcid.org/0000-0002-9628-4057
Eleftherios PelechasDivision of Rheumatology, Department of Medicine, School of Health Sciences, University of Ioannina, 45110, Ioannina, Greece.
Georgios ZouzosDivision of Rheumatology, Department of Medicine, School of Health Sciences, University of Ioannina, 45110, Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vasculitides are a cluster of diseases defined by an immune attack targeting vessels of different sizes. While most types of vasculitis have an undetermined cause, progress has been achieved in the recent decade in elucidating the mechanisms that participate in the inflammatory damage of the blood vessel wall. Several studies have emphasized that genetic susceptibility is an important aspect of the pathogenesis of vasculitides. The most prominent genetic risk loci for vasculitides reside within the major histocompatibility complex region. This indicates that the immune system is a major contributor to the pathogenesis of this group of diseases. In this chapter, we provide an updated overview of the etiology and pathogenesis of these entities with an emphasis on the major insights gained from recent genetic studies in the highly studied types of vasculitides.

Indexed as

ImmunogeneticsVasculitisGenetic Predisposition to DiseaseHumansMajor Histocompatibility ComplexGenetic riskGWASHLA associationsPathogenesisPrimary vasculitides

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.