ReviewCurrent pediatrics reports2022
Long-Term COVID 19 Sequelae in Adolescents: the Overlap with Orthostatic Intolerance and ME/CFS.
Review in Current pediatrics reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- No Causal Effects Detected in COVID-19 and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Two Sample Mendelian Randomization Study.International journal of environmental research and public health · 2023Pooled it
- Neurological and neurodevelopmental effects of Covid and MIS-C on children.Pediatric research · 2026Review
- Chronic fatigue syndrome in nursing practice: a concept analysis.BMC nursing · 2026Article
- Risks of autoimmune and inflammatory post-acute COVID-19 conditions: a network cohort study in six European countries, the USA and Korea.BMJ public health · 2026Article
- Chronic autonomic symptom burden in long-COVID: a follow-up cohort study.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- Berg Balance Scale in post-COVID-19 patients: results from a retrospective study.Journal of medicine and life · 2025Article
- Orthostatic Intolerance in Children With Long COVID Utilizing a 10-Minute Passive Standing Test.Clinical pediatrics · 2025Article
- Evaluation of a pediatric post-acute sequelae of SARS-CoV-2 index score.Frontiers in pediatrics · 2025Article
- Neuropsychological functioning of pediatric patients with long COVID.The Clinical neuropsychologist · 2024Article
- Longitudinal Fecal Microbiota Profiles in A Cohort of Non-Hospitalized Adolescents and Young Adults with COVID-19: Associations with SARS-CoV-2 Status and Long-Term Fatigue.Pathogens (Basel, Switzerland) · 2024Observational
- Using a novel methodology to map Post-COVID services for children and young people in England: a web-based systematic search.BMC health services research · 2024Article
- Cognitive disengagement syndrome in pediatric patients with long COVID: associations with mood, anxiety, and functional impairment.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2024Article
- Severe pediatric COVID-19: a review from the clinical and immunopathophysiological perspectives.World journal of pediatrics : WJP · 2024Review
- Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design.PloS one · 2024Observational
- New Alcohol Sensitivity in Patients With Post-acute Sequelae of SARS-CoV-2 (PASC): A Case Series.Cureus · 2023Article
- Pulmonary Evaluation in Children with Post-COVID-19 Condition Respiratory Symptoms: A Prospective Cohort Study.Journal of clinical medicine · 2023Article
- Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID?Journal of translational medicine · 2023Review
- Navigating paediatric virology through the COVID‑19 era (Review).International journal of molecular medicine · 2023Review
- Review
- Considerations in Children and Adolescents Related to Coronavirus Disease 2019 (COVID-19).Physical medicine and rehabilitation clinics of North America · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose of Review: To discuss emerging understandings of adolescent long COVID or post-COVID-19 conditions, including proposed clinical definitions, common symptoms, epidemiology, overlaps with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and orthostatic intolerance, and preliminary guidance on management. Recent Findings: The recent World Health Organization clinical case definition of post-COVID-19 condition requires a history of probable or confirmed SARS-CoV-2 infection, with symptoms starting within 3 months of the onset of COVID-19. Symptoms must last for at least 2 months and cannot be explained by an alternative diagnosis. Common symptoms of the post-COVID-19 condition include, but are not limited to, fatigue, shortness of breath, and cognitive dysfunction. These symptoms generally have an impact on everyday functioning. The incidence of prolonged symptoms following SARS-CoV-2 infection has proven challenging to define, but it is now clear that those with relatively mild initial infections, without severe initial respiratory disease or end-organ injury, can still develop chronic impairments, with symptoms that overlap with conditions like ME/CFS (profound fatigue, unrefreshing sleep, post-exertional malaise, cognitive dysfunction, and orthostatic intolerance). Summary: We do not yet have a clear understanding of the mechanisms by which individuals develop post-COVID-19 conditions. There may be several distinct types of long COVID that require different treatments. At this point, there is no single pharmacologic agent to effectively treat all symptoms. Because some presentations of post-COVID-19 conditions mimic disorders such as ME/CFS, treatment guidelines for this and related conditions can be helpful for managing post-COVID-19 symptoms. Supplementary Information: The online version contains supplementary material available at 10.1007/s40124-022-00261-4.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.