Evidence map›Paper›PMID 35293179›Full record

ArticleZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2022

[Effect of LOC103693069 on hypoxic apoptosis of bone marrow mesenchymal stem cells].

Chuan Wang, Fei Zhang, Wuxun Peng, Tao Wang, Zhihong Xie, Yanglin Yan, Hanke Qiu

Open access · greenAbstract read
In one paragraph

Article in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chuan WangEmergency Department, the Affiliated Hospital of Guizhou Medical University, Guiyang Guizhou, 550004, P. R. China.
Fei ZhangEmergency Department, the Affiliated Hospital of Guizhou Medical University, Guiyang Guizhou, 550004, P. R. China.
Wuxun PengEmergency Department, the Affiliated Hospital of Guizhou Medical University, Guiyang Guizhou, 550004, P. R. China.
Tao WangEmergency Department, the Affiliated Hospital of Guizhou Medical University, Guiyang Guizhou, 550004, P. R. China.
Zhihong XieEmergency Department, the Affiliated Hospital of Guizhou Medical University, Guiyang Guizhou, 550004, P. R. China.
Yanglin YanEmergency Department, the Affiliated Hospital of Guizhou Medical University, Guiyang Guizhou, 550004, P. R. China.
Hanke QiuEmergency Department, the Affiliated Hospital of Guizhou Medical University, Guiyang Guizhou, 550004, P. R. China.
Guiyang Medical University · CN

Funding

SUPPORT FOR THE ROSE F KENNEDY IDDRC P50P50HD105352 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SOPHIE MOLHOLM, Steven Upshaw Walkley · 2021 to 2026
$7.0M
NICHD NIH HHS P50 HD105352
6 · The paper itself

Abstract

Objective: To investigate the effect of LOC103693069 on hypoxic apoptosis of bone marrow mesenchymal stem cells (BMSCs). Methods: BMSCs from 1-week-old Sprague Dawley rat bone marrow were isolated, cultured, and passaged by the whole bone marrow adherent culture method. After identification of adipogenic, chondrogenic, and osteogenic differentiation, the 3rd generation cells were treated with hypoxia under 5%O Results: After cell viability, apoptosis, and apoptosis-related proteins were detected, cell apoptosis was the most significant under anaerobic conditions after 48 hours. The above indicators were significantly different from other groups ( Conclusion: LOC103693069 can relieve the hypoxic apoptosis of BMSCs.

Indexed as

Mesenchymal Stem CellsOsteogenesisAnimalsApoptosisBone Marrow CellsHypoxiaRatsRats, Sprague-DawleyBone marrow mesenchymal stem cellshypoxic apoptosislong non-coding RNArat

Identifiers

PMID35293179
PMCPMC8923933
OpenAlexW4221077398

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.