ArticleFrontiers in cardiovascular medicine2022
Association of Lean Body Mass and Fat Mass With 1-Year Mortality Among Patients With Heart Failure.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Association of predicted lean body mass and fat mass with prognosis in patients with heart failure preserved ejection fraction.PloS one · 2025Trial
- Total body water to lean body mass ratio predicts mortality in patients with chronic heart failure: a prospective, observational study.Frontiers in nutrition · 2026Article
- Impact of lean body mass index on short-term outcomes in patients with ischemic stroke: an observational cohort study.Scientific reports · 2025Observational
- Assessing Static Balance, Balance Confidence, and Fall Rate in Patients with Heart Failure and Preserved Ejection Fraction: A Comprehensive Analysis.Sensors (Basel, Switzerland) · 2024Article
- The role of body composition in left ventricular remodeling, reverse remodeling, and clinical outcomes for heart failure with mildly reduced ejection fraction: more knowledge to the "obesity paradox".Cardiovascular diabetology · 2024Article
- Depression Predicts Cardiac Cachexia in Heart Failure Patients.Biological research for nursing · 2023Article
- The role of predicted lean body mass and fat mass in non-alcoholic fatty liver disease in both sexes: Results from a secondary analysis of the NAGALA study.Frontiers in nutrition · 2023Article
- Body mass index at baseline directly predicts new-onset diabetes and to a lesser extent incident cardio-cerebrovascular events, but has a J-shaped relationship to all-cause mortality.BMC endocrine disorders · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Prior studies have found an unexplained inverse or U-shaped relationship between body mass index (BMI) and mortality in heart failure (HF) patients. However, little is known about the independent effects of each body component, i.e., lean body mass (LBM) and fat mass (FM), on mortality. Methods: We used data from the China Patient-centered Evaluative Assessment of Cardiac Events-Prospective Heart Failure Study. LBM and FM were calculated using equations developed from the National Health and Nutrition Examination Survey. LBM and FM index, calculated by dividing LBM or FM in kilograms by the square of height in meters, were used for analysis. We used restricted cubic spline and Cox model to examine the association of LBM and FM index with 1-year all-cause mortality. Results: Among 4,305 patients, median (interquartile range) age was 67 (57-76) years, 37.7% were women. During the 1-year follow-up, 691 (16.1%) patients died. After adjustments, LBM index was inversely associated with mortality in a linear way ( Conclusion: Higher LBM, not FM, was associated with lower 1-year mortality among HF patients.
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