Evidence map›Paper›PMID 35295582›Full record

ArticleFrontiers in physiology2022

Drivers of Sinoatrial Node Automaticity in Zebrafish: Comparison With Mechanisms of Mammalian Pacemaker Function.

Matthew R Stoyek, Eilidh A MacDonald, Melissa Mantifel, Jonathan S Baillie, Bailey M Selig, Roger P Croll, Frank M Smith, T Alexander Quinn

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Genes · 2024
    Article
  8. TheFrontiers in physiology · 2023
    Article
  9. Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Matthew R StoyekDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS, Canada.
Eilidh A MacDonaldDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS, Canada.
Melissa MantifelDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS, Canada.
Jonathan S BaillieDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS, Canada.
Bailey M SeligDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS, Canada.
Roger P CrollDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS, Canada.
Frank M SmithDepartment of Medical Neuroscience, Dalhousie University, Halifax, NS, Canada.
T Alexander QuinnDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS, Canada.
Dalhousie University · CAUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac excitation originates in the sinoatrial node (SAN), due to the automaticity of this distinct region of the heart. SAN automaticity is the result of a gradual depolarisation of the membrane potential in diastole, driven by a coupled system of transarcolemmal ion currents and intracellular Ca

Indexed as

autonomic nervous systemblebbistatincalcium clockheart rateleading pacemaker sitemechanics clockstretchvoltage clock

Identifiers

PMID35295582
PMCPMC8919049
OpenAlexW4214499286

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.