Evidence map›Paper›PMID 35296307›Full record

Trial reportBMC endocrine disorders2022

Efficacy of a pharmacist-managed diabetes clinic in high-risk diabetes patients, a randomized controlled trial - "Pharm-MD" : Impact of clinical pharmacists in diabetes care.

Alexandra Halalau, Melda Sonmez, Ahsan Uddin, Patrick Karabon, Zachary Scherzer, Scott Keeney

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC endocrine disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03377127 (PHARM-MD; An Open-Label, Randomized Controlled Phase II Study to Evaluate the Efficacy of a Pharmacist Managed Diabetes Clinic in High-Risk Diabetes Patients), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03377127 nacompletednot on this map

PHARM-MD; An Open-Label, Randomized Controlled Phase II Study to Evaluate the Efficacy of a Pharmacist Managed Diabetes Clinic in High-Risk Diabetes Patients

TypeinterventionalSponsorCorewell Health EastRan2018 to 2020Enrolled86ConditionsDiabetes Mellitus, Type 2ArmsPharmacy Managed Diabetes Clinic (PMDC), Standard of Care (SOC)
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. A mixed-methods approach to understanding pharmacists' experiences with the CANRISK diabetes risk questionnaire and user guide.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Effect on Diabetes Control in a Resident Clinic Following the Integration of a Clinic Pharmacist.Journal of community hospital internal medicine perspectives · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alexandra HalalauGeneral Internal Medicine Division, Beaumont Health, 3601 W 13 Mile Rd, Royal Oak, MI, USA. alexandra.halalau@beaumont.edu.
Melda SonmezInternal Medicine Department, Beaumont Health, Royal Oak, MI, USA.
Ahsan UddinMedicine- Pediatrics Department, Beaumont Health, Royal Oak, MI, USA.
Patrick KarabonOffice of Research, Oakland University William Beaumont School of Medicine, Rochester, MI, USA.
Zachary ScherzerOakland University William Beaumont School of Medicine, Rochester, MI, USA.
Scott KeeneyApogee Physicians, Erie, Philadelphia, USA.
Beaumont Health · USOakland University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus affects 13% of American adults. To address the complex care requirements necessary to avoid diabetes-related morbidity, the American Diabetes Association recommends utilization of multidisciplinary teams. Research shows pharmacists have a positive impact on multiple clinical diabetic outcomes.

methodsOpen-label randomized controlled trial with 1:1 assignment that took place in a single institution resident-run outpatient medicine clinic. Patients 18-75 years old with type 2 diabetes mellitus and most recent HbA1c ≥9% were randomized to standard of care (SOC) (continued with routine follow up with their primary provider) or to the SOC + pharmacist-managed diabetes clinic PMDC group (had an additional 6 visits with the pharmacist within 6 months from enrollment). Patients were followed for 12 months after enrollment. Data collected included HbA1c, lipid panel, statin use, blood pressure control, immunization status, and evidence of diabetic complications (retinopathy, nephropathy, neuropathy). Intention-to-treat and per-protocol analysis were performed.

resultsForty-four patients were enrolled in the SOC + PMDC group and 42 patients in the SOC group. Average decrease in HbA1c for the intervention compared to the control group at 6 months was - 2.85% vs. -1.32%, (p = 0.0051). Additionally, the odds of achieving a goal HbA1c of ≤8% at 6 months was 3.15 (95% CI = 1.18, 8.42, p = 0.0222) in the intervention versus control group. There was no statistically significant difference in the remaining secondary outcomes measured.

conclusionsAddition of pharmacist managed care for patients with type 2 diabetes mellitus is associated with significant improvements in HbA1c compared with standard of care alone. Missing data during follow up limited the power of secondary outcomes analyses.

trial registrationClinicalTrials.gov , ID: NCT03377127 ; first posted on 19/12/2017.

Indexed as

Outcome and Process Assessment, Health CarePharmacistsAdultAgedDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedOutpatient Clinics, HospitalDiabetesHemoglobin A1cManaged carePharmacy

Identifiers

PMID35296307
PMCPMC8925057
OpenAlexW4220722584

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.