Evidence map›Paper›PMID 35300324›Full record

ReviewFrontiers in immunology2022

Inflammatory Microenvironment of Skin Wounds.

Zhen Wang, Fang Qi, Han Luo, Guangchao Xu, Dali Wang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 173 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Surgical Humidification (HumiGardGlobal spine journal · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Inflammatory Stewardship-A Perspective for Active Management of Acute Inflammation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhen WangDepartment of Plastic Surgery and Burns, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Fang QiDepartment of Plastic Surgery and Burns, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Han LuoDepartment of Plastic Surgery and Burns, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Guangchao XuDepartment of Plastic Surgery and Burns, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Dali WangDepartment of Plastic Surgery and Burns, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Affiliated Hospital of Zunyi Medical College · CNZunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing is a dynamic and highly regulated process that can be separated into three overlapping and interdependent phases: inflammation, proliferation, and remodelling. This review focuses on the inflammation stage, as it is the key stage of wound healing and plays a vital role in the local immune response and determines the progression of wound healing. Inflammatory cells, the main effector cells of the inflammatory response, have been widely studied, but little attention has been paid to the immunomodulatory effects of wound healing in non-inflammatory cells and the extracellular matrix. In this review, we attempt to deepen our understanding of the wound-healing microenvironment in the inflammatory stage by focusing on the interactions between cells and the extracellular matrix, as well as their role in regulating the immune response during the inflammatory stage. We hope our findings will provide new ideas for promoting tissue regeneration through immune regulation.

Indexed as

Soft Tissue InjuriesWound HealingExtracellular MatrixHumansImmunomodulationInflammationextracellular matrixinflammatory cellsinflammatory microenvironmentnon-inflammatory cellswound healing

Identifiers

PMID35300324
PMCPMC8920979
OpenAlexW4214503795

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.