Evidence mapPaperPMID 35300378Full record

Trial reportFrontiers in cellular and infection microbiology2022

Effects of Konjaku Flour on the Gut Microbiota of Obese Patients.

Yu Li, Yongbo Kang, Yuhui Du, Minghui Chen, Liqiong Guo, Xinwei Huang, Tingting Li, Shi Chen, Fan Yang, Fubing Yu and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Effect ofFrontiers in nutrition · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Frontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Yu LiMedical Faculty, Kunming University of Science and Technology, Kunming, China.
Yongbo KangSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, China.
Yuhui DuMedical Faculty, Kunming University of Science and Technology, Kunming, China.
Minghui ChenMedical Faculty, Kunming University of Science and Technology, Kunming, China.
Liqiong GuoMedical Faculty, Kunming University of Science and Technology, Kunming, China.
Xinwei HuangMedical Faculty, Kunming University of Science and Technology, Kunming, China.
Tingting LiMedical Faculty, Kunming University of Science and Technology, Kunming, China.
Shi ChenMedical Faculty, Kunming University of Science and Technology, Kunming, China.
Fan YangNutrition Department, The First People's Hospital of Yunnan Province, Kunming, China.
Fubing YuDepartment of Gastroenterology, The Second People's Hospital of Yunnan Province, Kunming, China.
Jingan HongNutrition Department, The First People's Hospital of Yunnan Province, Kunming, China.
Xiangyang KongMedical Faculty, Kunming University of Science and Technology, Kunming, China.
Kunming University of Science and Technology · CNFirst People's Hospital of Yunnan Province · CNSouthern University of Science and Technology · CNSecond People's Hospital of Yunnan Province · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Gut microbiota have been thought to play a role in the emergence of obesity and metabolic disorders, thus dietary fiber may be an effective strategy for the management of obesity by modulating the gut microbiota. The aim of the present study was to investigate the effects of konjaku flour (KF) supplementation on treating obesity and regulating intestinal microbiota in obese adults. Methods: In a 5-week, randomized, double-blind, place-controlled trial, sixty-nine obese volunteers aged 25 to 35 with body mass index ≥28 kg/m Results: KF remarkably reduced the body mass index (BMI), fat mass, percentage body fat (PBF), serum triglyceride (TG), glycated hemoglobin A1c (HbA1c), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) levels in the patients ( Conclusion: These results suggested that KF can achieve positive effects on treating obesity, which manifest on reducing BMI, fat mass, blood glucose, and blood lipid, improving hepatic function, and also regulating intestinal microfloral structure. Therefore, changes in gut microbiota may explain in part the effects of KF.

Indexed as

Gastrointestinal MicrobiomeAdultBody Mass IndexFlourHumansObesityWeight Lossblood parametersgut microbiotakonjaku flourobesityobesity index

Identifiers

PMID35300378
PMCPMC8921482
OpenAlexW4214612342

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.