Evidence map›Paper›PMID 35301863›Full record

ArticleJournal of the American Heart Association2022

MicroRNAs Regulate TASK-1 and Are Linked to Myocardial Dilatation in Atrial Fibrillation.

Felix Wiedmann, Manuel Kraft, Stefan Kallenberger, Antonius Büscher, Amelie Paasche, Pablo L Blochberger, Timon Seeger, Natasa Jávorszky, Gregor Warnecke, Rawa Arif and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

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  18. Non-coding RNA and arrhythmias: expression, function, and molecular mechanism.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Review
  19. Noncoding RNAs as Key Regulators for Cardiac Development and Cardiovascular Diseases.Journal of cardiovascular development and disease · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Felix WiedmannDepartment of Cardiology Heidelberg University Hospital Heidelberg Germany.
Manuel KraftDepartment of Cardiology Heidelberg University Hospital Heidelberg Germany.
Stefan KallenbergerDigital Health Center Berlin Institute of Health (BIH) and Charité Berlin Germany.
Antonius BüscherDepartment for Cardiology II: Electrophysiology University Hospital Münster Münster Germany.
Amelie PaascheDepartment of Cardiology Heidelberg University Hospital Heidelberg Germany.ORCID 0000-0001-6882-1428
Pablo L BlochbergerDepartment of Cardiology Heidelberg University Hospital Heidelberg Germany.ORCID 0000-0003-1453-3134
Timon SeegerDepartment of Cardiology Heidelberg University Hospital Heidelberg Germany.
Natasa JávorszkyDepartment of Cardiology Heidelberg University Hospital Heidelberg Germany.
Gregor WarneckeDepartment of Cardiac Surgery University of Heidelberg Germany.
Rawa ArifDepartment of Cardiac Surgery University of Heidelberg Germany.
Jamila KremerDepartment of Cardiac Surgery University of Heidelberg Germany.ORCID 0000-0002-4660-6660
Matthias KarckDepartment of Cardiac Surgery University of Heidelberg Germany.
Norbert FreyDepartment of Cardiology Heidelberg University Hospital Heidelberg Germany.
Constanze SchmidtDepartment of Cardiology Heidelberg University Hospital Heidelberg Germany.ORCID 0000-0001-5897-237X
Heidelberg University · DEUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. However, underlying molecular mechanisms are insufficiently understood. Previous studies suggested that microRNA (miRNA) dependent gene regulation plays an important role in the initiation and maintenance of AF. The 2-pore-domain potassium channel TASK-1 (tandem of P domains in a weak inward rectifying K

Indexed as

Atrial FibrillationInduced Pluripotent Stem CellsMicroRNAsNerve Tissue ProteinsPotassium Channels, Tandem Pore DomainDilatationHeart AtriaHumansMicroRNAsNerve Tissue ProteinsPotassium Channels, Tandem Pore Domainpotassium channel subfamily K member 3atrial fibrillationion channel regulationKCNK3miRNATASK‐1

Identifiers

PMID35301863
PMCPMC9075420
OpenAlexW4220661130

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.