Evidence mapPaperPMID 35303930Full record

ArticleJournal of translational medicine2022

Exploring the translational challenge for medical applications of ionising radiation and corresponding radiation protection research.

Sophie Bockhold, Shane J Foley, Louise A Rainford, Riccardo Corridori, Annika Eberstein, Christoph Hoeschen, Mark W Konijnenberg, Susan Molyneux-Hodgson, Graciano Paulo, Joana Santos and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 6 countries.

Sophie BockholdRadiography and Diagnostic Imaging, School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland. sophie.bockhold@ucd.ie.
Shane J FoleyRadiography and Diagnostic Imaging, School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
Louise A RainfordRadiography and Diagnostic Imaging, School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
Riccardo CorridoriCOCIR, Brussels, Belgium.
Annika EbersteinCOCIR, Brussels, Belgium.
Christoph HoeschenInstitute of Medical Engineering, Otto Von Guericke Universität Magdeburg, Magdeburg, Germany.
Mark W KonijnenbergDepartment of Radiology and Nuclear Medicine, Erasmus Medical Centre, Rotterdam, Netherlands.
Susan Molyneux-HodgsonNuclear Societies Research Group, University of Exeter, Exeter, UK.
Graciano PauloEscola Superior de Tecnologia da Saúde, Instituto Politécnico de Coimbra, Coimbra, Portugal.
Joana SantosEscola Superior de Tecnologia da Saúde, Instituto Politécnico de Coimbra, Coimbra, Portugal.
Jonathan P McNultyRadiography and Diagnostic Imaging, School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
University College Dublin · IEEuropean Remanufacturing Council · BEPolytechnic Institute of Coimbra · PTErasmus University Rotterdam · NLOtto-von-Guericke University Magdeburg · DEUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedical applications of ionising radiation and associated radiation protection research often encounter long delays and inconsistent implementation when translated into clinical practice. A coordinated effort is needed to analyse the research needs for innovation transfer in radiation-based high-quality healthcare across Europe which can inform the development of an innovation transfer framework tailored for equitable implementation of radiation research at scale.

methodsBetween March and September 2021 a Delphi methodology was employed to gain consensus on key translational challenges from a range of professional stakeholders. A total of three Delphi rounds were conducted using a series of electronic surveys comprised of open-ended and closed-type questions. The surveys were disseminated via the EURAMED Rocc-n-Roll consortium network and prominent medical societies in the field. Approximately 350 professionals were invited to participate. Participants' level of agreement with each generated statement was captured using a 6-point Likert scale. Consensus was defined as median ≥ 4 with ≥ 60% of responses in the upper tertile of the scale. Additionally, the stability of responses across rounds was assessed.

resultsIn the first Delphi round a multidisciplinary panel of 20 generated 127 unique statements. The second and third Delphi rounds recruited a broader sample of 130 individuals to rate the extent to which they agreed with each statement as a key translational challenge. A total of 60 consensus statements resulted from the iterative Delphi process of which 55 demonstrated good stability. Ten statements were identified as high priority challenges with ≥ 80% of statement ratings either 'Agree' or 'Strongly Agree'.

conclusionA lack of interoperability between systems, insufficient resources, unsatisfactory education and training, and the need for greater public awareness surrounding the benefits, risks, and applications of ionising radiation were identified as principal translational challenges. These findings will help to inform a tailored innovation transfer framework for medical radiation research.

Indexed as

Radiation ProtectionConsensusDelphi TechniqueHumansRadiation, IonizingSurveys and QuestionnairesDelphi studyIonising radiationRadiation protectionTranslational medical research

Identifiers

PMID35303930
PMCPMC8932076
OpenAlexW4220747656

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.