Evidence map›Paper›PMID 35306877›Full record

ArticlemSphere2022

Control of Variant Surface Glycoprotein Expression by CFB2 in Trypanosoma brucei and Quantitative Proteomic Connections to Translation and Cytokinesis.

Gustavo Bravo Ruiz, Michele Tinti, Melanie Ridgway, David Horn

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gustavo Bravo RuizThe Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.ORCID 0000-0003-1550-1126
Michele TintiThe Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.ORCID 0000-0002-0051-017X
Melanie RidgwayThe Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.ORCID 0000-0002-6763-2366
David HornThe Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.ORCID 0000-0001-5173-9284
University of Dundee · GB

Funding

Wellcome Trust 097945/B/11/ZWellcome Trust 101842/Z13/ZWellcome Trust 217105/Z/19/Z
6 · The paper itself

Abstract

Variant surface glycoproteins (VSGs) coat parasitic African trypanosomes and underpin antigenic variation and immune evasion. These VSGs are superabundant virulence factors that are subject to posttranscriptional gene expression controls mediated via the

Indexed as

Trypanosoma brucei brucei3' Untranslated RegionsCytokinesisMembrane GlycoproteinsProteomicsRibosomal ProteinsRNA, Messenger3' Untranslated RegionsMembrane GlycoproteinsRibosomal ProteinsRNA, MessengermRNA bindingproteomicsRNAiTrypanosoma brucei

Identifiers

PMID35306877
PMCPMC9044945
OpenAlexW4220860562

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.