Evidence map›Paper›PMID 35311495›Full record

ArticleThe Libyan journal of medicine2022

Effects of vitamin C and D on the mRNA expression of angiotensin converting enzyme 2 receptor, cathepsin L, and transmembrane serine protease in the mouse lungs.

Meshref A Alruwaili, Yazun Jarrar

Open access · goldAbstract read
In one paragraph

Article in The Libyan journal of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Meshref A AlruwailiDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Skaka, Saudi Arabia.
Yazun JarrarDepartment of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan.
Al Jouf University · SAAl-Zaytoonah University of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamins (Vit) C and D are widely used as immunogenic supplements among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients. The SAR-CoV-2 virus enters into the pulmonary endothelial cells through attachment to angiotensin converting enzyme 2 receptor (Ace2) and the proteolytic activity of Cathepsin L (Ctsl) and transmembrane serine protease 2 (Tmprss2) enzymes. This study aimed to determine the influence of Vit C and D on the mRNA expression of

Indexed as

COVID-19Serine ProteasesAngiotensin-Converting Enzyme 2AnimalsAscorbic AcidCathepsin LEndothelial CellsHumansLungMicePeptidyl-Dipeptidase ARNA, MessengerSARS-CoV-2VitaminsAngiotensin-Converting Enzyme 2Ascorbic AcidCathepsin LPeptidyl-Dipeptidase ARNA, MessengerSerine ProteasesVitaminsAce2COVID-19lungsSARS-CoV-2vitamin Cvitamin D

Identifiers

PMID35311495
PMCPMC8942545
OpenAlexW4220768682

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.