Evidence map›Paper›PMID 35311588›Full record

ArticleMolecular and cellular biology2022

Purification and Identification of Natural Inhibitors of Protein Arginine Methyltransferases from Plants.

Zhengxin Wang, Ling Xiong, Quanbo Xiong

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Zhengxin WangCenter for Cancer Research and Therapeutic Development, Department of Biological Sciences, Clark Atlanta Universitygrid.254275.3, Atlanta, Georgia, USA.ORCID 0000-0002-7721-7326
Ling XiongCenter for Cancer Research and Therapeutic Development, Department of Biological Sciences, Clark Atlanta Universitygrid.254275.3, Atlanta, Georgia, USA.
Quanbo XiongCorteva Agriscience, Indianapolis, Indiana, USA.
Center for Cancer Research · USCorteva (United States) · US

Funding

To Investigate Molecular Mechanisms of Aging-Related Growth of the Prostate - Implications in Prostate Tumorigenesis and Cancer TreatmentU54MD007590 · NIMHD · CLARK ATLANTA UNIVERSITY · PI Geou-Yarh Liou · 2019 to 2026
$17.1M
Technologies/Resources for Core LaboratoriesG12MD007590 · NIMHD · CLARK ATLANTA UNIVERSITY · PI KHAN, SHAFIQ A · 2012 to 2018
$7.6M
Molecular mechanisms of the age-related re-growth of the prostateR15AG056867 · NIA · CLARK ATLANTA UNIVERSITY · PI WANG, ZHENGXIN · 2018 to 2018
$462k
NIA NIH HHS R15 AG056867NIMHD NIH HHS G12 MD007590NIMHD NIH HHS U54 MD007590
6 · The paper itself

Abstract

Protein arginine methyltransferase (PRMT) enzymes catalyze posttranslational modifications of target proteins and are often upregulated in human cancers. In this study, we purified two chemical compounds from seeds of

Indexed as

HistonesProtein-Arginine N-MethyltransferasesArginineHumansMaleMethylationMolecular Docking SimulationArginineHistonesPRMT5 protein, humanProtein-Arginine N-Methyltransferasesnatural compoundspheophorbideprotein arginine methyltransferase inhibitorsprotoporphyrintetrapyrrole macrocycle

Identifiers

PMID35311588
PMCPMC9022574
OpenAlexW4221052029

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.