Evidence map›Paper›PMID 35314614›Full record

ReviewNon-coding RNA2022

ABHD11-AS1: An Emerging Long Non-Coding RNA (lncRNA) with Clinical Significance in Human Malignancies.

Upendarrao Golla, Kishore Sesham, Siva Dallavalasa, Naresh Kumar Manda, Sambamoorthy Unnam, Arun Kumar Sanapala, Sharada Nalla, Susmitha Kondam, Rajesh Kumar

Open access · goldAbstract readReview
In one paragraph

Review in Non-coding RNA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  17. RNA Modifications Meet Tumors.Cancer management and research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Upendarrao GollaDepartment of Medicine, Division of Hematology and Oncology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.ORCID 0000-0003-0519-7087
Kishore SeshamDepartment of Anatomy, All India Institute of Medical Sciences (AIIMS), Mangalagiri 522503, India.
Siva DallavalasaCenter of Excellence in Molecular Biology and Regenerative Medicine (CEMR), Department of Biochemistry, JSS Medical College, Mysuru 570015, India.
Naresh Kumar MandaDepartment of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad 500046, India.ORCID 0000-0003-1751-8415
Sambamoorthy UnnamFaculty of Pharmacy, Sree Dattha Institute of Pharmacy, Ibrahimpatnam 501510, India.
Arun Kumar SanapalaFaculty of Pharmacy, Sree Dattha Institute of Pharmacy, Ibrahimpatnam 501510, India.
Sharada NallaFaculty of Pharmacy, University College of Pharmaceutical Sciences, Palamuru University, Mahabubnagar 509001, India.
Susmitha KondamFaculty of Pharmacy, University College of Pharmaceutical Sciences, Palamuru University, Mahabubnagar 509001, India.
Rajesh KumarDepartment of Anatomy, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India.ORCID 0000-0002-8743-7541
Palamuru University · INAll India Institute of Medical Sciences · INAll India Institute of Medical Sciences Raipur · INJSS Medical College and Hospital · INPennsylvania State University · USUniversity of Hyderabad · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aberrant expression of lncRNAs has been linked to the development and progression of different cancers. One such lncRNA is ABHD11 antisense RNA 1 (ABHD11-AS1), which has recently gained attention for its significant role in human malignancies. ABHD11-AS1 is highly expressed in gastric, lung, breast, colorectal, thyroid, pancreas, ovary, endometrium, cervix, and bladder cancers. Several reports highlighted the clinical significance of ABHD11-AS1 in prognosis, diagnosis, prediction of cancer progression stage, and treatment response. Significantly, the levels of ABHD11-AS1 in gastric juice had been exhibited as a clinical biomarker for the assessment of gastric cancer, while its serum levels have prognostic potential in thyroid cancers. The ABHD11-AS1 has been reported to exert oncogenic effects by sponging different microRNAs (miRNAs), altering signaling pathways such as PI3K/Akt, epigenetic mechanisms, and N6-methyladenosine (m

Indexed as

ABHD11-AS1biomarkercancerepigeneticslncRNAmiRNAN6-methyladenosinePI3K/Aktsignaling pathwaystranscription

Identifiers

PMID35314614
PMCPMC8938790
OpenAlexW4214946979

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.