Evidence map›Paper›PMID 35314653›Full record

ReviewInfectious disease reports2022

COVID-19 and the Endocrine System: A Review of the Current Information and Misinformation.

Samir Ahmed Mirza, Abdul Ahad Ehsan Sheikh, Michaela Barbera, Zainab Ijaz, Muhammad Ali Javaid, Rahul Shekhar, Suman Pal, Abu Baker Sheikh

Open access · goldAbstract readReview
In one paragraph

Review in Infectious disease reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. COVID-19 vaccines and blood glucose control: Friend or foe?Human vaccines & immunotherapeutics · 2024
    Review
  11. Review
  12. Article
  13. Implications of Dysnatremia and Endocrine Disturbances in COVID-19 Patients.International journal of molecular sciences · 2024
    Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Syncytin-1, syncytin-2 and suppressyn in human health and disease.Journal of molecular medicine (Berlin, Germany) · 2023
    Review
  19. Article
  20. Pituitary and SARS CoV-2: An unremitting conundrum.Best practice & research. Clinical endocrinology & metabolism · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Samir Ahmed MirzaDepartment of Internal Medicine, Dow Medical College, Karachi 74200, Pakistan.
Abdul Ahad Ehsan SheikhDepartment of Internal Medicine, The Wright Center for Graduate Medical Education, Scranton, PA 18505, USA.
Michaela BarberaDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM 87106, USA.
Zainab IjazDepartment of Psychiatry, William Beaumont Hospital, Royal Oak, MI 48073, USA.ORCID 0000-0003-3157-1933
Muhammad Ali JavaidDepartment of Internal Medicine, Dow Medical College, Karachi 74200, Pakistan.
Rahul ShekharDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM 87106, USA.
Suman PalDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM 87106, USA.ORCID 0000-0002-2051-9788
Abu Baker SheikhDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM 87106, USA.ORCID 0000-0003-0503-6961
University of New Mexico · USDow University of Health Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) infection primarily involves the respiratory system but has many noteworthy extra pulmonary manifestations as well. We write this review to highlight the basis of some pathophysiological mechanisms of COVID-19 infection-induced endocrine dysfunction. Different scientific databases and institutional websites were searched to collect and consolidate the most up-to-date data relating to COVID-19 infection and endocrine systems. Hypopituitarism, central diabetes insipidus, SIADH, thyroid abnormalities, hyperglycemia, adrenal insufficiency, orchitis and alteration in sperm morphology have been reported in case reports of patients with COVID-19 infection. Data focusing on COVID-19 vaccination was also searched to summarize the effect, if any, on the endocrine system. Endocrinopathies noted post COVID-19 vaccination, including cases of adrenal hemorrhage, new onset Type II Diabetes Mellitus and subacute thyroiditis, are also discussed in this review. This review calls attention to the misinformation relating to COVID-19 vaccination with supposed endocrine effects such as infertility and problems with pregnancy. Rebutting these misconceptions can help increase compliance and maximize COVID-19 vaccination to the public.

Indexed as

adrenalcoronavirus 2019COVID-19diabetesendocrinefertilityhypothalamusmisinformationpancreaspituitarythyroidvaccine

Identifiers

PMID35314653
PMCPMC8938795
OpenAlexW4221113703

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.