Evidence map›Paper›PMID 35316352›Full record

ArticleJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2023

Ablation of FAM20C caused short root defects via suppressing the BMP signaling pathway in mice.

Lili Li, Peihong Liu, Xuechao Lv, Tianliang Yu, Xingai Jin, Rui Wang, Xiaohua Xie, Qingshan Wang, Yingqun Liu, Wuliji Saiyin

Abstract read
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In one paragraph

Article in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lili LiDepartment of Stomatology, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Road, Nangang, 150086, Harbin, Heilongjiang, China.ORCID http://orcid.org/0000-0002-9298-3192
Peihong LiuDepartment of Stomatology, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Road, Nangang, 150086, Harbin, Heilongjiang, China.
Xuechao LvDepartment of Stomatology, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Road, Nangang, 150086, Harbin, Heilongjiang, China.
Tianliang YuDepartment of Stomatology, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Road, Nangang, 150086, Harbin, Heilongjiang, China.
Xingai JinDepartment of Stomatology, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Road, Nangang, 150086, Harbin, Heilongjiang, China.
Rui WangDepartment of Stomatology, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Road, Nangang, 150086, Harbin, Heilongjiang, China.
Xiaohua XieInstitute of Hard Tissue Development and Regeneration, The Second Affiliated Hospital of Harbin Medical University, 150001, Harbin, Heilongjiang, China.
Qingshan WangDepartment of Vascular Surgery, The Heilongjiang Provincial Hospital, 82 Zhongshan Road, Xiangfang, 150036, Harbin, Heilongjiang, China.
Yingqun LiuDepartment of Stomatology, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Road, Nangang, 150086, Harbin, Heilongjiang, China.
Wuliji SaiyinDepartment of Stomatology, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Road, Nangang, 150086, Harbin, Heilongjiang, China. iamwuliji@163.com.ORCID http://orcid.org/0000-0001-9062-5028
Harbin Medical University · CNHeilongjiang Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Short root defects are prone to cause various periodontal diseases and lead to tooth loss in some serious cases. Studies about the mechanisms governing the development of the root are needed for a better understanding of the pathogenesis of short root defects. The protein family with sequence similarity 20 group C (FAM20C) is a Golgi casein kinase that has been well studied in the development of tooth crown formation. However, whether FAM20C plays a role in the development of tooth root is still unknown. Thus, we generated Sox2-Cre;Fam20c

Indexed as

Bone morphogenetic protein signalingCell proliferationConditional knockout mouse modelOdontoblast differentiationTooth root

Identifiers

PMID35316352
OpenAlexW4220652134

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.