Evidence map›Paper›PMID 35316551›Full record

SynthesisDermatologic therapy2022

A systematic review on mucocutaneous presentations after COVID-19 vaccination and expert recommendations about vaccination of important immune-mediated dermatologic disorders.

Farnoosh Seirafianpour, Homa Pourriyahi, Milad Gholizadeh Mesgarha, Arash Pour Mohammad, Zoha Shaka, Azadeh Goodarzi

Abstract readSystematic Review
In one paragraph

Synthesis in Dermatologic therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Oral Lesions Following Anti-SARS-CoV-2 Vaccination: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
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  6. Article
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  11. Article
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  13. Vitiligo Repigmentation After SARS-CoV-2 Vaccine.Dermatology practical & conceptual · 2023
    Article
  14. Article
  15. Review
  16. Review
  17. Nonepisodic angioedema with eosinophilia after COVID-19 vaccination: a case successfully treated with reslizumab.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Farnoosh SeirafianpourStudent Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Homa PourriyahiStudent Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Milad Gholizadeh MesgarhaFaculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Arash Pour MohammadStudent Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Zoha ShakaFaculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Azadeh GoodarziDepartment of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-1249-4429

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With dermatologic side effects being fairly prevalent following vaccination against COVID-19, and the multitude of studies aiming to report and analyze these adverse events, the need for an extensive investigation on previous studies seemed urgent, in order to provide a thorough body of information about these post-COVID-19 immunization mucocutaneous reactions. To achieve this goal, a comprehensive electronic search was performed through the international databases including Medline (PubMed), Scopus, Cochrane, Web of science, and Google scholar on July 12, 2021, and all articles regarding mucocutaneous manifestations and considerations after COVID-19 vaccine administration were retrieved using the following keywords: COVID-19 vaccine, dermatology considerations and mucocutaneous manifestations. A total of 917 records were retrieved and a final number of 180 articles were included in data extraction. Mild, moderate, severe and potentially life-threatening adverse events have been reported following immunization with COVID vaccines, through case reports, case series, observational studies, randomized clinical trials, and further recommendations and consensus position papers regarding vaccination. In this systematic review, we categorized these results in detail into five elaborate tables, making what we believe to be an extensively informative, unprecedented set of data on this topic. Based on our findings, in the viewpoint of the pros and cons of vaccination, mucocutaneous adverse events were mostly non-significant, self-limiting reactions, and for the more uncommon moderate to severe reactions, guidelines and consensus position papers could be of great importance to provide those at higher risks and those with specific worries of flare-ups or inefficient immunization, with sufficient recommendations to safely schedule their vaccine doses, or avoid vaccination if they have the discussed contra-indications.

Indexed as

COVID-19COVID-19 VaccinesHumansMucous MembraneSkinVaccinationCOVID-19 Vaccinesacuteadverse effectadverse eventadverse event following immunizationallergyangioedemaAstraZenecaAstraZeneca/Oxfordatopic dermatitisBharatcollagen vascular diseaseComirnatyCOVID-19 vaccinecutaneouscyanosisdelayeddelayed-type hypersensitivitydermatologyecchymosisedemaerythema multiformeexanthematous rashherpeshidradenitis suppurativainflammatory bowel diseaseinjection site reactionJanssenJohnson & Johnsonlatelocal site reactionmaculopapular rashmastocytosisModernamorbilliform rashmucocutaneousmucosalpemphigoidpemphigusPernioPetechiaPfizerPfizer-BioNTechpityriasis roseaprurituspsoriasispurpuraremote site reactionrheumatic disordersSARS-Cov-2side effectSinopharmSinovacSputnikurticariavaccineVaccine Adverse Event Reporting Systemzoster

Identifiers

PMID35316551
PMCPMC9111423

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.