ArticleArchives of medical science : AMS2022
miRNA-21 plays an important role in necrotizing enterocolitis.
Article in Archives of medical science : AMS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- DNAzyme-RCA-based colorimetric and lateral flow dipstick assays for the point-of-care testing of exosomal m5C-miRNA-21.Chemical science · 2024Article
- MiRNA-192-5p-targeted activated leukocyte cell adhesion molecule improved inflammatory injury of neonatal necrotizing enterocolitis.Pediatric surgery international · 2024Article
- Novel scoring system for early diagnosis of necrotizing enterocolitis: integrating clinical and laboratory data with urinary caveolin-1 levels.Archives of medical science : AMS · 2024Article
- Decoding the Promise and Challenges of miRNA-Based Cancer Therapies: An Essential Update on miR-21, miR-34, and miR-155.International journal of medical sciences · 2024Review
- Oxymatrine inhibits the development of radioresistance in NSCLC cells by reversing EMT through the DcR3/AKT/GSK-3β pathway.Archives of medical science : AMS · 2024Article
- Chromatin as alarmins in necrotizing enterocolitis.Frontiers in immunology · 2024Review
- Necrotizing enterocolitis in premature infants-A defect in the brakes? Evidence from clinical and animal studies.Mucosal immunology · 2023Review
- Biomarkers of necrotizing enterocolitis in the era of machine learning and omics.Seminars in perinatology · 2023Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: To investigate the role and mechanism of miRNA-21 in necrotizing enterocolitis (NEC). Material and methods: Collecting 30 pairs of newborn and NEC children and measuring the miRNA-21 expression in the serum of 30 pairs. Thirty neonatal Wistar rats were randomized to 3 groups: NC, Model and miRNA groups. The rats of model and miRNA groups were based on NEC model groups, after the fabricated NEC model of neonatal rats. The Model group was treated with normal saline and the miRNA group was injected with miRNA-21 from the abdomen. On the 4 Results: In the clinical data, the miRNA-21 gene expression of NEC children was significantly up-regulation compared with that of normal newborns ( Conclusions: miRNA might be a biological marker and therapeutic target in NEC diagnosis and treatment.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.