SynthesisArchives of medical research2022
COVID-19 in Neonates with Positive RT-PCR Test. Systematic Review.
Synthesis in Archives of medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mother-to-child transmission of SARS-CoV-2 infection in high-income countries: a systematic review and meta-analysis of prospective observational studies.Scientific reports · 2023Pooled it
- Development of a prediction model for infant hospitalisation and death using clinical features assessed by community health workers during routine postnatal home visits in Dhaka, Bangladesh.BMJ paediatrics open · 2026Article
- Mechanistic insights into the impact of prenatal viral infections on maternal and offspring immunity.Npj viruses · 2026Review
- Severe infection incidence among young infants in Dhaka, Bangladesh: an observational cohort study.BMJ public health · 2025Article
- [Expert recommendations for the prevention of common respiratory viral infections in neonates].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
- Differences in clinical characteristics of early-onset and late-onset severe acute respiratory syndrome coronavirus 2 infections in neonates.European journal of pediatrics · 2024Article
- Newborn Hospitalizations Before and During COVID-19 Pandemic in Poland: A Comparative Study Based on a National Hospital Registry.International journal of public health · 2024Article
- Hybrid Diagnostic Model for Improved COVID-19 Detection in Lung Radiographs Using Deep and Traditional Features.Biomimetics (Basel, Switzerland) · 2023Article
- [Clinical characteristics of neonates infected with the Omicron variant of SARS-CoV-2: a multicenter cross-sectional survey].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- [Clinical features of 23 neonates infected with Omicron variant of severe acute respiratory syndrome coronavirus 2].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- Antibiotic Overprescribing among Neonates and Children Hospitalized with COVID-19 in Pakistan and the Implications.Antibiotics (Basel, Switzerland) · 2023Article
- A multicentre study on the clinical characteristics of newborns infected with coronavirus disease 2019 during the omicron wave.Frontiers in pediatrics · 2023Article
- Functional consequences of SARS-CoV-2 infection in pregnant women, fetoplacental unit, and neonate.Biochimica et biophysica acta. Molecular basis of disease · 2023Review
- Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2.Talanta · 2023Article
- First Neonates with Vertical Transmission of SARS-CoV-2 Infection in Late Pregnancy in West Part of Romania: Case Series.Diagnostics (Basel, Switzerland) · 2022Article
- Extracorporeal membrane oxygenation in the care of a preterm infant with COVID-19 infection: Case report.Frontiers in pediatrics · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCOVID-19 is an infectious disease of variable severity caused by a new coronavirus. Clinical presentation ranges from asymptomatic cases to severe illness. Most cases in newborns appear to be asymptomatic or mild.
objectiveTo conduct a systematic review of the literature on published studies of COVID-19 in newborns with a positive RT-PCR test.
methodsThe PubMed and EMBASE databases were searched for infection data in newborns from 1 December 2019-21 May 2021. The mesh terms included "SARS-CoV-2", "COVID-19", "novel coronavirus", "newborns" and "neonates". The selection criteria were as follows: original studies reporting clinical, radiological, laboratory, and outcome data in newborns with a positive RT-PCR test for SARS-CoV-2. Two independent investigators reviewed the studies.
resultsSeventy-two studies that involved 236 newborns were included. The main clinical manifestations were fever (43.2%), respiratory (46.6%), and gastrointestinal (35.2%) symptoms; 60.1% had mild/moderate disease. A total of 52.5% had a chest X-ray; 43.5% were normal, and 24.1% reported consolidation/infiltration images. The most frequent laboratory abnormalities were elevated C reactive protein and elevated procalcitonin and lymphopenia. Mortality was 1.7%.
conclusionSymptoms of SARS-CoV-2 infection were mild to moderate in most of the newborns. The prognosis was good, and mortality was mainly associated with other comorbidities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.