ArticleNature2022
Inhibition of calcium-triggered secretion by hydrocarbon-stapled peptides.
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Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
9.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 72 citations in OpenAlex.
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- Synergistic regulation of fusion pore opening and dilation by SNARE and synaptotagmin-1.Journal of molecular cell biology · 2024Article
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- Emerging cell and molecular targets for treating mucus hypersecretion in asthma.Allergology international : official journal of the Japanese Society of Allergology · 2024Review
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- Mucus hypersecretion in chronic obstructive pulmonary disease: From molecular mechanisms to treatment.Journal of translational internal medicine · 2023Article
- The release of inhibition model reproduces kinetics and plasticity of neurotransmitter release in central synapses.Communications biology · 2023Article
Corrections and comments
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Authors and funding
15 authors at 8 institutions in 3 countries.
Ying LaiDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA. ylai@scu.edu.cn.
Giorgio FoisInstitute of General Physiology, Ulm University, Ulm, Germany.ORCID http://orcid.org/0000-0001-5414-1149
Jose R FloresDepartment of Pulmonary Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Michael J TuvimDepartment of Pulmonary Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID http://orcid.org/0000-0001-8126-7716
Qiangjun ZhouDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-1789-9588
Kailu YangDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-8234-1997
Jeremy LeitzDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.
John PetersDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-3192-7824
Yunxiang ZhangDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.
Richard A PfuetznerDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.
Luis EsquiviesDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.
Philip JonesInstitute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Manfred FrickInstitute of General Physiology, Ulm University, Ulm, Germany. manfred.frick@uni-ulm.de.ORCID http://orcid.org/0000-0002-4763-1104
Burton F DickeyDepartment of Pulmonary Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA. bdickey@mdanderson.org.
Axel T BrungerDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA. brunger@stanford.edu.ORCID http://orcid.org/0000-0001-5121-2036
Howard Hughes Medical Institute · USThe University of Texas MD Anderson Cancer Center · USUniversität Ulm · DEFudan University · CNHarvard University · USSichuan University · CNStanford University · USVanderbilt University · US
Funding
Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8MSTRUCTURE OF PROTEINS INVOLVED IN SYNAPTIC EXOCYTOSISR01MH063105 · NIMH · STANFORD UNIVERSITY · PI BRUNGER, AXEL T · 2000 to 2025
$4.7MSingle molecule studies of SNARE-induced vesicle fusionR37MH063105 · NIMH · STANFORD UNIVERSITY · PI BRUNGER, AXEL T · 2011 to 2020
$4.7MControlling the core airway mucin secretion machinery to prevent pathophysiologyR01HL129795 · NHLBI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DICKEY, BURTON F · 2015 to 2023
$3.8MMolecular Mechanism and Regulation of Asynchronous ReleaseR00MH113764 · NIMH · VANDERBILT UNIVERSITY · PI ZHOU, QIANGJUN · 2020 to 2022
$719kRoles of Synaptotagmin-2 in Airway ObstructionR21AI137319 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ADACHI, ROBERTO · 2018 to 2019
$440kMolecular Mechanism and Regulation of Asynchronous ReleaseK99MH113764 · NIMH · STANFORD UNIVERSITY · PI ZHOU, QIANGJUN · 2017 to 2018
$223kNCI NIH HHS P30 CA016672NHLBI NIH HHS R01 HL129795NIAID NIH HHS R21 AI137319NIMH NIH HHS K99 MH113764NIMH NIH HHS R00 MH113764NIMH NIH HHS R01 MH063105NIMH NIH HHS R37 MH063105
Abstract
Membrane fusion triggered by Ca
Indexed as
CalciumHydrocarbonsMembrane FusionMucinsSNARE ProteinsAnimalsMiceNeurotransmitter AgentsPeptidesRespiratory MucosaCalciumHydrocarbonsMucinsNeurotransmitter AgentsPeptidesSNARE Proteins
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.