Evidence map›Paper›PMID 35322421›Full record

ArticleImmunology2022

Adoptive transfer of IL-4 reprogrammed Tc17 cells elicits anti-tumour immunity through functional plasticity.

Chiung-Hui Liu, Bo-Shiou Lin, Mei-Yao Wu, Ying-Chyi Song, Tao-Wei Ke, Yu-Lun Chou, Chuan-Teng Liu, Chia-Hsin Lin, Vedran Radojcic, Charles Drake and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Chiung-Hui LiuDepartment of Anatomy, Faculty of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Bo-Shiou LinResearch Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Mei-Yao WuResearch Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Ying-Chyi SongResearch Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Tao-Wei KeDepartment of Colorectal Surgery, China Medical University Hospital, Taichung, Taiwan.
Yu-Lun ChouResearch Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Chuan-Teng LiuResearch Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Chia-Hsin LinResearch Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Vedran RadojcicDivision of Hematology & Hematologic Malignancies, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Charles DrakeColumbia Center for Translational Immunology, Columbia University Irving Medical Center, New York, New York, USA.
Hung-Rong YenResearch Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.ORCID 0000-0002-0131-1658
China Medical University · TWAsia University · TWColumbia University Irving Medical Center · USUniversity of Utah · US

Funding

Probing Notch regulation of alloimmunity to uncover novel strategies for graft-versus-host disease controlK08HL145116 · NHLBI · UNIVERSITY OF UTAH · PI RADOJCIC, VEDRAN · 2019 to 2020
$350k
NHLBI NIH HHS K08 HL145116
6 · The paper itself

Abstract

Ability of IL-17-producing CD8

Indexed as

CD8-Positive T-LymphocytesInterleukin-4Adoptive TransferAnimalsHumansInterleukin-17MicePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktInterleukin-17Interleukin-4Phosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktadoptive cell therapyEomesIL-17IL-4Tc17T cell reprogrammingTrat1

Identifiers

PMID35322421
PMCPMC11558351
OpenAlexW4220823764

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.