ArticleThe New phytologist2022
Inactivation of the entire Arabidopsis group II GH3s confers tolerance to salinity and water deficit.
Article in The New phytologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 64 citations in OpenAlex.
- Metabolism meets transport: a new perspective on auxin homeostasis at subcellular level.Planta · 2026Review
- GH3 phylogenetic subgroups define divergent routes of auxin inactivation via aspartate and glutamine conjugation.Plant physiology · 2026Article
- Comprehensive characterisation of IAA inactivation pathways reveals the impact of glycosylation on auxin metabolism and plant development in Arabidopsis.Communications biology · 2026Article
- Transcriptomic changes associated with heat-induced susceptibility in wheat plants to Hessian fly (Diptera: Cecidomyiidae).Frontiers in plant science · 2026Article
- Pretreatment with Silver Thiosulfate Increases the Auxin-Inductive Effect for Rooting Mature Chestnut Shoots.Plants (Basel, Switzerland) · 2025Article
- Response of hidden architects to salt stress.Planta · 2025Review
- Evolution analysis of GH3 gene family in five Rosaceae species and FaGH3.17, FaGH3.18 improve drought tolerance in transgenic Arabidopsis.BMC plant biology · 2025Article
- Engineering saline-alkali-tolerant apple rootstock by knocking down MdGH3 genes in M9-T337.Stress biology · 2025Article
- Arabidopsis GH3.10 conjugates jasmonates.Plant biology (Stuttgart, Germany) · 2025Article
- Salt Stress Leads to Morphological and Transcriptional Changes in Roots of Pumpkins (Plants (Basel, Switzerland) · 2025Article
- Inactivation of GH3.5 by COP1-mediated K63-linked ubiquitination promotes seedling hypocotyl elongation.Nature communications · 2025Article
- Integration of GWAS and transcriptome analysis to identify temperature-dependent genes involved in germination of rapeseed (Frontiers in plant science · 2025Article
- Dinor-12-oxo-phytodienoic acid conjugation with amino acids inhibits its phytohormone bioactivity in Marchantia polymorpha.Plant physiology · 2024Article
- Comparative Physiological and Transcriptomics Profiling Provides Integrated Insight into Melatonin Mediated Salt and Copper Stress Tolerance inPlants (Basel, Switzerland) · 2024Article
- Article
- Comprehensive Morphological and Molecular Insights into Drought Tolerance Variation at Germination Stage inPlants (Basel, Switzerland) · 2024Article
- Slow release of a synthetic auxin induces formation of adventitious roots in recalcitrant woody plants.Nature biotechnology · 2024Article
- Phytohormones and related genes function as physiological and molecular switches regulating water stress response in the sunflower.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Molecular and physiological responses to salt stress in salinity-sensitive and tolerant Hibiscus rosa-sinensis cultivars.Molecular horticulture · 2023Article
- The Roles of GRETCHEN HAGEN3 (GH3)-Dependent Auxin Conjugation in the Regulation of Plant Development and Stress Adaptation.Plants (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Indole-3-acetic acid (IAA) controls a plethora of developmental processes. Thus, regulation of its concentration is of great relevance for plant performance. Cellular IAA concentration depends on its transport, biosynthesis and the various pathways for IAA inactivation, including oxidation and conjugation. Group II members of the GRETCHEN HAGEN 3 (GH3) gene family code for acyl acid amido synthetases catalysing the conjugation of IAA to amino acids. However, the high degree of functional redundancy among them has hampered thorough analysis of their roles in plant development. In this work, we generated an Arabidopsis gh3.1,2,3,4,5,6,9,17 (gh3oct) mutant to knock out the group II GH3 pathway. The gh3oct plants had an elaborated root architecture, showed an increased tolerance to different osmotic stresses, including an IAA-dependent tolerance to salinity, and were more tolerant to water deficit. Indole-3-acetic acid metabolite quantification in gh3oct plants suggested the existence of additional GH3-like enzymes in IAA metabolism. Moreover, our data suggested that 2-oxindole-3-acetic acid production depends, at least in part, on the GH3 pathway. Targeted stress-hormone analysis further suggested involvement of abscisic acid in the differential response to salinity of gh3oct plants. Taken together, our data provide new insights into the roles of group II GH3s in IAA metabolism and hormone-regulated plant development.
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