Evidence map›Paper›PMID 35323042›Full record

ReviewmBio2022

The HIV Env Glycoprotein Conformational States on Cells and Viruses.

Connie Zhao, Hongru Li, Talia H Swartz, Benjamin K Chen

Open access · goldAbstract readReview
In one paragraph

Review in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Connie Zhao *Department of Medicine, Icahn School of Medicine at Mount Sinaigrid.59734.3c, New York, New York, USA.
Hongru Li *Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinaigrid.59734.3c, New York, New York, USA.
Talia H SwartzDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinaigrid.59734.3c, New York, New York, USA.ORCID 0000-0003-1572-045X
Benjamin K ChenDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinaigrid.59734.3c, New York, New York, USA.ORCID 0000-0002-5404-1997
Icahn School of Medicine at Mount Sinai · US

Funding

HIV immune evasion and escape through T cell virological synapsesR37AI148064 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BENJAMIN K CHEN · 2022 to 2026
$3.1M
Elucidating the mechanisms of cannabinoids on HIV-1 infection and inflammasome activationR01DA052255 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SWARTZ, TALIA H · 2020 to 2024
$2.1M
Cell migration and virological synapse formation in parenteral HIV transmissionR01DA041765 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHEN, BENJAMIN K · 2016 to 2020
$2.1M
Mechanisms of efficient HIV infection through T cell virological synapsesR01GM113885 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHEN, BENJAMIN K · 2014 to 2017
$1.7M
HIV immune evasion and escape through T cell virological synapsesR56AI148064 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHEN, BENJAMIN K · 2020 to 2020
$538k
NIAID NIH HHS R37 AI148064NIAID NIH HHS R56 AI148064NIDA NIH HHS R01 DA041765NIDA NIH HHS R01 DA052255NIGMS NIH HHS R01 GM113885
6 · The paper itself

Abstract

The HIV Env glycoprotein is the surface glycoprotein responsible for viral entry into CD4

Indexed as

HIV-1HIV InfectionsCD4 Antigensenv Gene Products, Human Immunodeficiency VirusHIV AntibodiesHumansProtein ConformationCD4 Antigensenv Gene Products, Human Immunodeficiency VirusHIV AntibodiesconformationendocytosisEnvenvelopeHIVneutralizing antibodiesprotein traffickingvirological synapse

Identifiers

PMID35323042
PMCPMC9040720
OpenAlexW4220719141

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.