Evidence map›Paper›PMID 35324428›Full record

ArticleeLife2022

Beneficial impacts of neuromuscular electrical stimulation on muscle structure and function in the zebrafish model of Duchenne muscular dystrophy.

Elisabeth A Kilroy, Amanda C Ignacz, Kaylee L Brann, Claire E Schaffer, Devon Varney, Sarah S Alrowaished, Kodey J Silknitter, Jordan N Miner, Ahmed Almaghasilah, Tashawna L Spellen and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Modeling neuromuscular diseases in zebrafish.Frontiers in molecular neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Elisabeth A KilroyGraduate School of Biomedical Science and Engineering, University of Maine, Orono, United States.
Amanda C IgnaczGraduate School of Biomedical Science and Engineering, University of Maine, Orono, United States.
Kaylee L BrannSchool of Biology and Ecology, University of Maine, Orono, United States.
Claire E SchafferSchool of Biology and Ecology, University of Maine, Orono, United States.
Devon VarneySchool of Biology and Ecology, University of Maine, Orono, United States.
Sarah S AlrowaishedSchool of Biology and Ecology, University of Maine, Orono, United States.
Kodey J SilknitterGraduate School of Biomedical Science and Engineering, University of Maine, Orono, United States.
Jordan N MinerDepartment of Chemical and Biomedical Engineering, University of Maine, Orono, United States.ORCID 0000-0003-2998-3330
Ahmed AlmaghasilahGraduate School of Biomedical Science and Engineering, University of Maine, Orono, United States.
Tashawna L SpellenSchool of Biology and Ecology, University of Maine, Orono, United States.
Alexandra D LewisSchool of Biology and Ecology, University of Maine, Orono, United States.
Karissa TilburyGraduate School of Biomedical Science and Engineering, University of Maine, Orono, United States.
Benjamin L KingGraduate School of Biomedical Science and Engineering, University of Maine, Orono, United States.
Joshua B KelleyGraduate School of Biomedical Science and Engineering, University of Maine, Orono, United States.
Clarissa A HenryGraduate School of Biomedical Science and Engineering, University of Maine, Orono, United States.ORCID 0000-0001-7204-9231
University of Maine · US

Funding

Mechanisms of NAD+ action during muscle development and homeostasis in a zebrafish dystroglycanopathy modelR01AR075836 · NIAMS · UNIVERSITY OF MAINE ORONO · PI HENRY, CLARISSA A · 2019 to 2023
$1.6M
Neuromuscular development in a zebrafish dystroglycanopathy modelR15HD099018 · NICHD · UNIVERSITY OF MAINE ORONO · PI HENRY, CLARISSA A · 2019 to 2019
$432k
The role of G alpha signaling in gradient trackingR15GM128026 · NIGMS · UNIVERSITY OF MAINE ORONO · PI KELLEY, JOSHUA BRIAN, KHALIL, ANDRE · 2018 to 2018
$424k
NIAMS NIH HHS R01 AR075836NICHD NIH HHS R15 HD099018NIGMS NIH HHS R15 GM128026
6 · The paper itself

Abstract

Neuromuscular electrical stimulation (NMES) allows activation of muscle fibers in the absence of voluntary force generation. NMES could have the potential to promote muscle homeostasis in the context of muscle disease, but the impacts of NMES on diseased muscle are not well understood. We used the zebrafish Duchenne muscular dystrophy (

Indexed as

Muscular Dystrophy, DuchenneAnimalsElectric StimulationHumansMuscle, SkeletalNeuromuscular JunctionZebrafishdevelopmental biologydystroglycanopathiesneuromuscular developmentskeletal musclezebrafish

Identifiers

PMID35324428
PMCPMC8947762
OpenAlexW4220764212

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.