Evidence map›Paper›PMID 35324664›Full record

ReviewToxins2022

Mycotoxins' Toxicological Mechanisms Involving Humans, Livestock and Their Associated Health Concerns: A Review.

Chinaza Godseill Awuchi, Erick Nyakundi Ondari, Sarah Nwozo, Grace Akinyi Odongo, Ifie Josiah Eseoghene, Hannington Twinomuhwezi, Chukwuka U Ogbonna, Anjani K Upadhyay, Ademiku O Adeleye, Charles Odilichukwu R Okpala

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 2 pooled it
39.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 211 citations in OpenAlex.

  1. Pooled it
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  17. In vitro adsorption of Fumonisin BMycotoxin research · 2026
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Chinaza Godseill AwuchiDepartment of Biochemistry, Kampala International University, Bushenyi P.O. Box 20000, Uganda.ORCID 0000-0001-5071-8895
Erick Nyakundi OndariDepartment of Biochemistry, Kampala International University, Bushenyi P.O. Box 20000, Uganda.ORCID 0000-0002-1498-6486
Sarah NwozoDepartment of Biochemistry, Kampala International University, Bushenyi P.O. Box 20000, Uganda.
Grace Akinyi OdongoDepartment of Biochemistry, Kampala International University, Bushenyi P.O. Box 20000, Uganda.
Ifie Josiah EseogheneDepartment of Biochemistry, Kampala International University, Bushenyi P.O. Box 20000, Uganda.ORCID 0000-0002-2714-3322
Hannington TwinomuhweziDepartment of Chemistry, Kyambogo University, Kyambogo, Kampala P.O. Box 1, Uganda.
Chukwuka U OgbonnaDepartment of Biochemistry, Federal University of Agriculture, P.M.B. 2240, Abeokuta 110124, Ogun State, Nigeria.ORCID 0000-0003-2073-9374
Anjani K UpadhyayHeredity Healthcare & Lifesciences, 206-KIIT TBI, Patia, Bhubaneswar 751024, Odisha, India.
Ademiku O AdeleyeFaith Heroic Generation, No. 36 Temidire Street, Azure 340251, Ondo State, Nigeria.ORCID 0000-0003-0197-810X
Charles Odilichukwu R OkpalaDepartment of Functional Foods Product Development, Wrocław University of Environmental and Life Sciences, 51-630 Wrocław, Poland.ORCID 0000-0003-4475-8887
Kampala International University · UGFederal University of Agriculture · NGKyambogo University · UGWrocław University of Environmental and Life Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycotoxins are well established toxic metabolic entities produced when fungi invade agricultural/farm produce, and this happens especially when the conditions are favourable. Exposure to mycotoxins can directly take place via the consumption of infected foods and feeds; humans can also be indirectly exposed from consuming animals fed with infected feeds. Among the hundreds of mycotoxins known to humans, around a handful have drawn the most concern because of their occurrence in food and severe effects on human health. The increasing public health importance of mycotoxins across human and livestock environments mandates the continued review of the relevant literature, especially with regard to understanding their toxicological mechanisms. In particular, our analysis of recently conducted reviews showed that the toxicological mechanisms of mycotoxins deserve additional attention to help provide enhanced understanding regarding this subject matter. For this reason, this current work reviewed the mycotoxins' toxicological mechanisms involving humans, livestock, and their associated health concerns. In particular, we have deepened our understanding about how the mycotoxins' toxicological mechanisms impact on the human cellular genome. Along with the significance of mycotoxin toxicities and their toxicological mechanisms, there are associated health concerns arising from exposures to these toxins, including DNA damage, kidney damage, DNA/RNA mutations, growth impairment in children, gene modifications, and immune impairment. More needs to be done to enhance the understanding regards the mechanisms underscoring the environmental implications of mycotoxins, which can be actualized via risk assessment studies into the conditions/factors facilitating mycotoxins' toxicities.

Indexed as

LivestockMycotoxinsAnimalsFood ContaminationFungiHumansMycotoxinsdiseasehealth risksmoldsmycotoxicosismycotoxins

Identifiers

PMID35324664
PMCPMC8949390
OpenAlexW4214542462

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.