Evidence map›Paper›PMID 35325402›Full record

ReviewCurrent oncology reports2022

The Role of Hyperthermia in the Treatment of Peritoneal Surface Malignancies.

Carlos E Guerra-Londono, Carlos G Tarazona, J A Sánchez-Monroy, Olivia Heppell, Juan J Guerra-Londono, Rupen Shah

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlos E Guerra-LondonoDepartment of Anesthesiology, Pain Management, & Perioperative Medicine, Henry Ford Health System, 2850 W. Grand Blvd, 4th Floor, Detroit, MI, 48202, USA. Cguerra1@hfhs.org.ORCID 0000-0002-5227-6047
Carlos G TarazonaDepartamento de Física, Universidad Nacional de Colombia, Av. Carrera 30 # 45-03 Edif. 404, Bogotá, D.C., Colombia, 111321.
J A Sánchez-MonroyDepartamento de Física, Universidad Nacional de Colombia, Av. Carrera 30 # 45-03 Edif. 404, Bogotá, D.C., Colombia, 111321.
Olivia HeppellWayne State University School of Medicine, 540 E. Canfield Ave., Detroit, MI, 48201, USA.
Juan J Guerra-LondonoFacultad de Medicina, Universidad Nacional de Colombia, Carrera 30 No. 45-03 Edif. 471, Bogotá, D.C., Colombia, 111321.
Rupen ShahDepartment of Surgery, Henry Ford Health System, 2799 W. Grand Blvd, Detroit, MI, 48202, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewHyperthermia is used to treat peritoneal surface malignancies (PSM), particularly during hyperthermic intraperitoneal chemotherapy (HIPEC). This manuscript provides a focused update of hyperthermia in the treatment of PSM. RECENT

findingsThe heterogeneous response to hyperthermia in PSM can be explained by tumor and treatment conditions. PSM tumors may resist hyperthermia via metabolic and immunologic adaptation. The thermodynamics of HIPEC are complex and require computational fluid dynamics (CFD). The clinical evidence supporting the benefit of hyperthermia is largely observational. Continued research will allow clinicians to characterize and predict the individual response of PSM to hyperthermia. The application of hyperthermia in current HIPEC protocols is mostly empirical. Thus, modeling heat transfer with CFD is a necessary task if we are to achieve consistent and reproducible hyperthermia. Although observational evidence suggests a survival benefit of hyperthermia, no clinical trial has tested the individual role of hyperthermia in PSM.

Indexed as

Hyperthermia, InducedPeritoneal NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsCombined Modality TherapyCytoreduction Surgical ProceduresHumansHyperthermic Intraperitoneal ChemotherapyCancer treatmentHeat transferHyperthermiaHyperthermic intraperitoneal chemotherapyPeritoneal cancerPeritoneal surface malignancyPrognosisSurvivalThermodynamic model

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.