Evidence mapPaperPMID 35325848Full record

ReviewBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2022

Epidemiology, clinical ramifications, and cellular pathogenesis of COVID-19 mRNA-vaccination-induced adverse cardiovascular outcomes: A state-of-the-heart review.

Talal Almas, Sarah Rehman, Eyad Mansour, Tarek Khedro, Ali Alansari, Jahanzeb Malik, Norah Alshareef, Vikneswaran Raj Nagarajan, Abdulla Hussain Al-Awaid, Reema Alsufyani and 13 more

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. A new mRNA antigen vaccine induces potent B and T cell responses andbioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Arrhythmias after COVID-19 Vaccination: Have We Left All Stones Unturned?International journal of molecular sciences · 2023
    Review
  9. Article
  10. Review
  11. Observational
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 10 institutions in 4 countries.

Talal AlmasRoyal College of Surgeons in Ireland, Dublin, Ireland. Electronic address: talalalmas.almas@gmail.com.
Sarah RehmanAga Khan University, Karachi, Pakistan.
Eyad MansourRoyal College of Surgeons in Ireland, Dublin, Ireland.
Tarek KhedroRoyal College of Surgeons in Ireland, Dublin, Ireland.
Ali AlansariUniversity Hospital, National University of Ireland Galway, Galway, Ireland.
Jahanzeb MalikRawalpindi Institute of Cardiology, Rawalpindi, Pakistan.
Norah AlshareefRoyal College of Surgeons in Ireland, Dublin, Ireland.
Vikneswaran Raj NagarajanRoyal College of Surgeons in Ireland, Dublin, Ireland.
Abdulla Hussain Al-AwaidRoyal College of Surgeons in Ireland, Dublin, Ireland.
Reema AlsufyaniRoyal College of Surgeons in Ireland, Dublin, Ireland.
Majid AlsufyaniRoyal College of Surgeons in Ireland, Dublin, Ireland.
Ali RifaiRoyal College of Surgeons in Ireland, Dublin, Ireland.
Ahlam AlzahraniRoyal College of Surgeons in Ireland, Dublin, Ireland.
Dhineswaran Raj NagarajanSunway University School of Medicine and Health Science, Malaysia.
Tala AbdullatifNational University of Ireland, Galway, Ireland.
Varman GunasaegaramGalway University Hospital, Galway, Ireland.
Enaam AlzadjaliRoyal College of Surgeons in Ireland, Dublin, Ireland.
Arthi SubramanianRoyal College of Surgeons in Ireland, Dublin, Ireland.
Abida RahmanTrinity Centre for Global Health, Trinity College Dublin, Ireland.
Yasar SattarDepartment of Cardiology, West Virginia University, Morgantown, WV, USA.
Jason GaloHarrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Hafeez Ul Hassan VirkAdena Regional Medical Center, Chillicothe, OH, USA.
M Chadi AlraiesDepartment of Interventional Cardiology, Detroit Medical Center, DMC Heart Hospital, Detroit, MI, USA.
Royal College of Surgeons in Ireland · IEOllscoil na Gaillimhe – University of Galway · IEAdena Regional Medical Center · USAga Khan University · PKRawalpindi Medical University · PKSunway University · MYTrinity College Dublin · IEUniversity Hospital Galway · IEUniversity Hospitals of Cleveland · USWest Virginia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) has overwhelming healthcare systems globally. To date, a myriad of therapeutic regimens has been employed in an attempt to curb the ramifications of a severe COVID-19 infection. Amidst the ongoing pandemic, the advent and efficacious uptake of COVID-19 vaccination has significantly reduced disease-related hospitalizations and mortality. Nevertheless, many side-effects are being reported after COVID-19 vaccinations and myocarditis is the most commonly reported sequelae post vaccination. Majority of these diseases are associated with COVID-19 mRNA vaccines. Various studies have established a temporal relationship between these complications, yet the causality and the underlying pathogenesis remain hypothetical. In this review, we aim to critically appraise the available literature regarding the cardiovascular side effects of the various mRNA vaccines and the associated pathophysiology.

Indexed as

COVID-19COVID-19 VaccinesHumansRNA, MessengerSARS-CoV-2VaccinationCOVID-19 VaccinesRNA, MessengerCoronavirus 2019 (COVID-19)COVID-19 mRNA vaccineCOVID-19 myocarditisCOVID-19 perimyocarditisSARS-CoV-2Takotsubo syndrome

Identifiers

PMID35325848
PMCPMC8934717
OpenAlexW4220902933

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.