Evidence mapPaperPMID 35326461Full record

ReviewCells2022

Cardiovascular Inflammaging: Mechanisms and Translational Aspects.

Maria Luisa Barcena, Muhammad Aslam, Sofya Pozdniakova, Kristina Norman, Yury Ladilov

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Beyond the beats: a systematic review of the underlying inflammatory pathways between atrial fibrillation and cognitive decline.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Maria Luisa BarcenaDepartment of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.ORCID 0000-0003-1391-9262
Muhammad AslamExperimental Cardiology, Department of Internal Medicine I, Justus Liebig University, Aulweg 129, 35392 Giessen, Germany.ORCID 0000-0002-8529-4217
Sofya PozdniakovaDepartment of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.ORCID 0000-0001-5849-1787
Kristina NormanDepartment of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Yury LadilovDepartment of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.ORCID 0000-0002-9836-8801
Barcelona Biomedical Research Park · ESGerman Centre for Cardiovascular Research · DEJustus-Liebig-Universität Gießen · DEUniversitätsklinikum Brandenburg an der Havel · DEUniversity of Potsdam · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is one of the major non-reversible risk factors for several chronic diseases, including cancer, type 2 diabetes, dementia, and cardiovascular diseases (CVD), and it is a key cause of multimorbidity, disability, and frailty (decreased physical activity, fatigue, and weight loss). The underlying cellular mechanisms are complex and consist of multifactorial processes, such as telomere shortening, chronic low-grade inflammation, oxidative stress, mitochondrial dysfunction, accumulation of senescent cells, and reduced autophagy. In this review, we focused on the molecular mechanisms and translational aspects of cardiovascular aging-related inflammation, i.e., inflammaging.

Indexed as

Cellular SenescenceDiabetes Mellitus, Type 2HumansInflammationLungcardiac inflammagingmicrobiomemitochondrial homeostasisvascular senescence

Identifiers

PMID35326461
PMCPMC8946971
OpenAlexW4221111240

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.