ReviewCancers2022
Functional Decline in the Cancer Patient: A Review.
Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07694479 (A Habit-Based Intervention to Reduce Sedentary Behaviour in Cancer Survivors), which is not on this map. Cited by 77 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Habit-Based Intervention to Reduce Sedentary Behaviour in Cancer Survivors: A Feasibility Study
Who cites it
77 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Healthcare Professionals' Perceptions of Decision-Making for Older Patients with Cancer Receiving Systemic Therapy: A Systematic Review and Qualitative Evidence Synthesis.Annals of geriatric medicine and research · 2026Pooled it
- Treatment decision-making and quality of life versus length of life preferences of older patients with early stage cancer: A systematic review.Journal of geriatric oncology · 2025Pooled it
- Changes in quality of life throughout the illness trajectory of older adults with cancer: a systematic review.The oncologist · 2025Pooled it
- The prognostic role of Geriatric 8 in patients with cancer: a meta-analysis and systematic review.The oncologist · 2025Pooled it
- Trial
- Trial
- Implementing exercise and self-management for women with breast cancer during treatment: results of the NEXT-BRCA randomized controlled trial.Scientific reports · 2025Trial
- Vegetable Gardening and Health Outcomes in Older Cancer Survivors: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Primary Treatment Modification and Treatment Tolerability Among Older Chemotherapy Recipients With Advanced Cancer.JAMA network open · 2024Trial
- Supplementary motor area syndrome in intracranial gliomas is not associated with worse survival.Journal of neuro-oncology · 2026Article
- Wearable-derived postdischarge mobility as a digital biomarker for 90-day readmission and mortality in metastatic cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Using Patient-Reported Outcome Measures to Identify Mobility Limitation in Incurable Cancer.Archives of rehabilitation research and clinical translation · 2026Article
- The Senior Fitness Test for assessing functional fitness in cancer patients and survivors: a cross-sectional study.Scientific reports · 2026Article
- Relationship between incident cardiovascular disease and quality of life after a breast cancer diagnosis.Journal of cancer survivorship : research and practice · 2026Article
- The Interplay of Quality of Life and Satisfaction with Nursing Care in Cancer Patients: A Narrative Review.Clinics and practice · 2026Review
- Association between postoperative surgical site infection and oncologic outcomes in soft tissue sarcoma: a propensity score-matched analysis using the bone and soft tissue registry.International orthopaedics · 2026Article
- Fall-related injuries in older adult cancer survivors: a decade of racial disparities.BMC geriatrics · 2026Article
- Prevalence of physical functional impairments and associations with quality of life: a cross-sectional study in Chinese cancer survivors.BMC nursing · 2026Article
- A prospective multimethod investigation of cancer-related pain integrating clinical data and machine learning: results from the RUGGI Study.Journal of anesthesia, analgesia and critical care · 2026Article
- Navigating long-term patient-reported outcomes after colorectal cancer surgery in older adults: ostomy, nutritional status, and living conditions as determinants in a prospective cohort study.International journal of colorectal disease · 2026Observational
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
A decline in functional status, an individual's ability to perform the normal activities required to maintain adequate health and meet basic needs, is part of normal ageing. Functional decline, however, appears to be accelerated in older patients with cancer. Such decline can occur as a result of a cancer itself, cancer treatment-related factors, or a combination of the two. The accelerated decline in function seen in older patients with cancer can be slowed, or even partly mitigated through routine assessments of functional status and timely interventions where appropriate. This is particularly important given the link between functional decline and impaired quality of life, increased mortality, comorbidity burden, and carer dependency. However, a routine assessment of and the use of interventions for functional decline do not typically feature in the long-term care of cancer survivors. This review outlines the link between cancer and subsequent functional decline, as well as potential underlying mechanisms, the tools that can be used to assess functional status, and strategies for its prevention and management in older patients with cancer.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.