Evidence map›Paper›PMID 35328218›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Diencephalic Syndrome Due to Optic Pathway Gliomas in Pediatric Patients: An Italian Multicenter Study.

Lucia De Martino, Stefania Picariello, Silvia Triarico, Nicola Improda, Pietro Spennato, Michele Antonio Capozza, Anna Grandone, Claudia Santoro, Daniela Cioffi, Giorgio Attinà and 3 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Diencephalic Syndrome in Adolescents: A Case Series.Annals of the Child Neurology Society · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Lucia De MartinoNeurooncology Unit, Department of Pediatric Oncology, Santobono-Pausilipon Children's Hospital, via M. Fiore n° 6, 80129 Naples, Italy.
Stefania PicarielloNeurooncology Unit, Department of Pediatric Oncology, Santobono-Pausilipon Children's Hospital, via M. Fiore n° 6, 80129 Naples, Italy.ORCID 0000-0001-5013-1138
Silvia TriaricoPediatric Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli, 00168 Rome, Italy.ORCID 0000-0002-9271-4398
Nicola ImprodaEmergency Unit, Department of Emergency, Santobono-Pausilipon Children's Hospital, via M. Fiore n° 6, 80129 Naples, Italy.ORCID 0000-0003-4235-0917
Pietro SpennatoPediatric Neurosurgery Unit, Department of Pediatric Neurosciences, Santobono-Pausilipon Children's Hospital, via M. Fiore n° 6, 80129 Naples, Italy.ORCID 0000-0001-7758-8605
Michele Antonio CapozzaPediatric Oncology Unit, Department of Pediatric Oncology, Santobono-Pausilipon Children's Hospital, via Posillipo n° 226, 80123 Naples, Italy.
Anna GrandoneDepartment of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", via L. De Crecchio n° 2, 80138 Naples, Italy.
Claudia SantoroDepartment of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", via L. De Crecchio n° 2, 80138 Naples, Italy.ORCID 0000-0003-4547-0500
Daniela CioffiPediatric Endocrinology Unit, Department of Pediatrics, Santobono-Pausilipon Children's Hospital, via M. Fiore n° 6, 80129 Naples, Italy.
Giorgio AttinàPediatric Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli, 00168 Rome, Italy.ORCID 0000-0002-9053-8765
Giuseppe CinalliPediatric Neurosurgery Unit, Department of Pediatric Neurosciences, Santobono-Pausilipon Children's Hospital, via M. Fiore n° 6, 80129 Naples, Italy.ORCID 0000-0002-7797-8483
Antonio RuggieroPediatric Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli, 00168 Rome, Italy.ORCID 0000-0002-6052-3511
Lucia QuagliettaNeurooncology Unit, Department of Pediatric Oncology, Santobono-Pausilipon Children's Hospital, via M. Fiore n° 6, 80129 Naples, Italy.
Santobono Children's Hospital · ITAgostino Gemelli University Polyclinic · ITUniversity of Campania "Luigi Vanvitelli" · ITFederico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diencephalic syndrome (DS) is a rare pediatric condition associated with optic pathway gliomas (OPGs). Since they are slow-growing tumors, their diagnosis might be delayed, with consequences on long-term outcomes. We present a multicenter case series of nine children with DS associated with OPG, with the aim of providing relevant details about mortality and long-term sequelae. We retrospectively identified nine children (6 M) with DS (median age 14 months, range 3-26 months). Four patients had NF1-related OPGs. Children with NF1 were significantly older than sporadic cases (median (range) age in months: 21.2 (14-26) versus 10 (3-17);

Indexed as

chemotherapydiencephalic syndromelong-term outcomesNF1optic pathway gliomapediatric

Identifiers

PMID35328218
PMCPMC8947184
OpenAlexW4220657722

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.