Evidence map›Paper›PMID 35328531›Full record

ArticleInternational journal of molecular sciences2022

Structural Consequence of Non-Synonymous Single-Nucleotide Variants in the N-Terminal Domain of LIS1.

Ho Jin Choi, Sarmistha Mitra, Yeasmin Akter Munni, Raju Dash, Sarmin Ummey Habiba, Md Sohel, Sultana Israt Jahan, Tae Jung Jang, Il Soo Moon

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Ho Jin ChoiDepartment of Anatomy, Dongguk University College of Medicine, Gyeongju 38066, Korea.
Sarmistha MitraDepartment of Anatomy, Dongguk University College of Medicine, Gyeongju 38066, Korea.
Yeasmin Akter MunniDepartment of Anatomy, Dongguk University College of Medicine, Gyeongju 38066, Korea.ORCID 0000-0001-5232-7214
Raju DashDepartment of Anatomy, Dongguk University College of Medicine, Gyeongju 38066, Korea.ORCID 0000-0003-4128-5308
Sarmin Ummey HabibaDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.
Md SohelDepartment of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail 1902, Bangladesh.
Sultana Israt JahanDepartment of Biotechnology and Genetic Engineering, Noakhali Science and Technology University, Noakhali 3814, Bangladesh.
Tae Jung JangDepartment of Pathology, Dongguk University College of Medicine, Gyeongju 38066, Korea.
Il Soo MoonDepartment of Anatomy, Dongguk University College of Medicine, Gyeongju 38066, Korea.ORCID 0000-0002-1608-016X
Dongguk University · KRBGC Trust University Bangladesh · BDMawlana Bhashani Science and Technology University · BDNoakhali Science and Technology University · BD

Funding

National Research Foundation of Korea NRF-2021R1A2C1008564
6 · The paper itself

Abstract

Disruptive neuronal migration during early brain development causes severe brain malformation. Characterized by mislocalization of cortical neurons, this condition is a result of the loss of function of migration regulating genes. One known neuronal migration disorder is lissencephaly (LIS), which is caused by deletions or mutations of the

Indexed as

LissencephalyNervous System Malformations1-Alkyl-2-acetylglycerophosphocholine EsteraseDyneinsHumansMicrotubule-Associated ProteinsNucleotides1-Alkyl-2-acetylglycerophosphocholine EsteraseDyneinsMicrotubule-Associated ProteinsNucleotidesLIS1lissencephalymolecular dynamics simulationsingle nucleotide polymorphismsvariant

Identifiers

PMID35328531
PMCPMC8955593
OpenAlexW4221108660

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.