Evidence map›Paper›PMID 35328603›Full record

ArticleInternational journal of molecular sciences2022

Analysis of Multiple Drug Resistance Mechanism in Different Types of Soft Tissue Sarcomas: Assessment of the Expression of ABC-Transporters, MVP, YB-1, and Analysis of Their Correlation with Chemosensitivity of Cancer Cells.

Natalia I Moiseeva, Lidia A Laletina, Timur I Fetisov, Leyla F Makhmudova, Angelika E Manikaylo, Liliya Y Fomina, Denis A Burov, Ekaterina A Lesovaya, Beniamin Y Bokhyan, Victoria Y Zinovieva and 8 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Natalia I MoiseevaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.ORCID 0000-0001-6697-7154
Lidia A LaletinaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Timur I FetisovN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Leyla F MakhmudovaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Angelika E ManikayloN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Liliya Y FominaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Denis A BurovN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Ekaterina A LesovayaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.ORCID 0000-0002-1967-9637
Beniamin Y BokhyanN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.ORCID 0000-0002-1396-3434
Victoria Y ZinovievaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Alice S VilkovaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Larisa V MekhedaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Nikolay A KozlovN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.ORCID 0000-0003-3852-3969
Alexander M ScherbakovN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.ORCID 0000-0002-2974-9555
Evgeny M KirilinBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Gennady A BelitskyN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Marianna G YakubovskayaN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Kirill I KirsanovN.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.ORCID 0000-0002-8599-6833
Lomonosov Moscow State University · RUPeoples' Friendship University of Russia · RURyazan State Medical University named after Academician I.P. Pavlov · RU

Funding

Russian Foundation for Basic Research MK 18-29-09095
6 · The paper itself

Abstract

Chemotherapy of soft tissue sarcomas (STS) is restricted by low chemosensitivity and multiple drug resistance (MDR). The purpose of our study was the analysis of MDR mechanism in different types of STS. We assessed the expression of ABC-transporters,

Indexed as

SarcomaSoft Tissue NeoplasmsATP-Binding Cassette TransportersDocetaxelDrug Resistance, MultipleDrug Resistance, NeoplasmHumansNeoplasm Recurrence, LocalATP-Binding Cassette TransportersDocetaxelABCB1ABCC1ABCG2chemosensitivity testMVPPgpsoft tissue sarcomasynovial sarcomaundifferentiated pleomorphic sarcomaYB-1

Identifiers

PMID35328603
PMCPMC8951302
OpenAlexW4221016264

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.