Evidence map›Paper›PMID 35328674›Full record

ArticleInternational journal of molecular sciences2022

Early Alterations of Intra-Mural Elastic Lamellae Revealed by Synchrotron X-ray Micro-CT Exploration of Diabetic Aortas.

Aïcha Ben Zemzem, Xiaowen Liang, Laetitia Vanalderwiert, Camille Bour, Béatrice Romier-Crouzet, Sébastien Blaise, Michael J Sherratt, Timm Weitkamp, Manuel Dauchez, Stéphanie Baud and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Aïcha Ben ZemzemUMR MEDyC, CNRS 7369, Université de Reims Champagne Ardenne, SFR CAP SANTE, 51100 Reims, France.
Xiaowen LiangUMR MEDyC, CNRS 7369, Université de Reims Champagne Ardenne, SFR CAP SANTE, 51100 Reims, France.
Laetitia VanalderwiertUMR MEDyC, CNRS 7369, Université de Reims Champagne Ardenne, SFR CAP SANTE, 51100 Reims, France.
Camille BourUMR MEDyC, CNRS 7369, Université de Reims Champagne Ardenne, SFR CAP SANTE, 51100 Reims, France.
Béatrice Romier-CrouzetUMR MEDyC, CNRS 7369, Université de Reims Champagne Ardenne, SFR CAP SANTE, 51100 Reims, France.
Sébastien BlaiseUMR MEDyC, CNRS 7369, Université de Reims Champagne Ardenne, SFR CAP SANTE, 51100 Reims, France.
Michael J SherrattDivision of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester M13 9PT, UK.ORCID 0000-0003-4759-6617
Timm WeitkampSynchrotron SOLEIL, 91192 Gif-sur-Yvette, France.ORCID 0000-0002-0374-0472
Manuel DauchezUMR MEDyC, CNRS 7369, Université de Reims Champagne Ardenne, SFR CAP SANTE, 51100 Reims, France.ORCID 0000-0002-6743-7915
Stéphanie BaudUMR MEDyC, CNRS 7369, Université de Reims Champagne Ardenne, SFR CAP SANTE, 51100 Reims, France.ORCID 0000-0002-4436-0652
Nicolas PassatCReSTIC, Université de Reims Champagne Ardenne, 51100 Reims, France.
Laurent DebelleUMR MEDyC, CNRS 7369, Université de Reims Champagne Ardenne, SFR CAP SANTE, 51100 Reims, France.
Sébastien AlmagroUMR MEDyC, CNRS 7369, Université de Reims Champagne Ardenne, SFR CAP SANTE, 51100 Reims, France.ORCID 0000-0002-6974-1187
Centre National de la Recherche Scientifique · FRCentre de Recherche en Sciences et Technologies de l'Information et de la Communication · FRSynchrotron soleil · FRUniversity of Manchester · GB

Funding

Agence Nationale de la Recherche ANR-11-EQPX-0031chair MAgICS (Grand Reims, Université de Reims Champagne-Ardenne Chair MAgICSDRRT Champagne Ardenne Projet Incitatif AmontRégion Grand Est FHURégion Grand Est OMAGESoleil Synchrotron 20191028
6 · The paper itself

Abstract

Diabetes is a major concern of our society as it affects one person out of 11 around the world. Elastic fiber alterations due to diabetes increase the stiffness of large arteries, but the structural effects of these alterations are poorly known. To address this issue, we used synchrotron X-ray microcomputed tomography with in-line phase contrast to image in three dimensions C57Bl6J (control) and db/db (diabetic) mice with a resolution of 650 nm/voxel and a field size of 1.3 mm

Indexed as

Diabetes MellitusSynchrotronsAgedAnimalsAortaElasticityElastic TissueHumansMiceX-Ray Microtomographyaccelerated agingarterial walldiabeteselastic fibersextracellular matrixX-ray microtomography

Identifiers

PMID35328674
PMCPMC8954876
OpenAlexW4220825892

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.