Evidence map›Paper›PMID 35328769›Full record

ReviewInternational journal of molecular sciences2022

Pathophysiology of Atherosclerosis.

Shifa Jebari-Benslaiman, Unai Galicia-García, Asier Larrea-Sebal, Javier Rekondo Olaetxea, Iraide Alloza, Koen Vandenbroeck, Asier Benito-Vicente, César Martín

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07659951 (The Effect of Motivational Interviewing on Healthy Lifestyle Behaviors and Biochemical Parameters in Patients Undergoing Stent Implantation After Coronary Angiography), which is not on this map. Cited by 511 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
511citing papers in PubMed, 5 pooled it
66.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07659951 nacompletednot on this mapstarted 2025, after this paper: background citation

The Effect of Motivational Interviewing on Healthy Lifestyle Behaviors and Biochemical Parameters in Patients Undergoing Stent Implantation After Coronary Angiography

TypeinterventionalSponsorBiruni UniversityRan2025 to 2026Enrolled55ConditionsCoronary Artery DiseaseArmsMotivational Interviewing
3 · Its place in the literature

Who cites it

511 citing papers in PubMed, 5 syntheses or guidelines pooled it, 844 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Early atherogenesis: In search of etiology.International journal of cardiology. Cardiovascular risk and prevention · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Macrophage PIM1 Drives Atherosclerosis by Enhancing Foam Cell Formation Via CD36.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Olfactomedin 2 Promotes Atherosclerosis by Eliciting Smooth Muscle Foam Cell Formation.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Article

451 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shifa Jebari-BenslaimanDepartment of Biochemistry and Molecular Biology, Universidad del País Vasco UPV/EHU, 48940 Leioa, Bizkaia, Spain.
Unai Galicia-GarcíaBiofisika Institute (UPV/EHU, CSIC), Barrio Sarriena s/n., 48940 Leioa, Bizkaia, Spain.
Asier Larrea-SebalBiofisika Institute (UPV/EHU, CSIC), Barrio Sarriena s/n., 48940 Leioa, Bizkaia, Spain.
Javier Rekondo OlaetxeaCardiology Department, Basurto University Hospital, 48013 Bilbao, Bizkaia, Spain.
Iraide AllozaDepartment of Biochemistry and Molecular Biology, Universidad del País Vasco UPV/EHU, 48940 Leioa, Bizkaia, Spain.
Koen VandenbroeckDepartment of Biochemistry and Molecular Biology, Universidad del País Vasco UPV/EHU, 48940 Leioa, Bizkaia, Spain.
Asier Benito-VicenteDepartment of Biochemistry and Molecular Biology, Universidad del País Vasco UPV/EHU, 48940 Leioa, Bizkaia, Spain.
César MartínDepartment of Biochemistry and Molecular Biology, Universidad del País Vasco UPV/EHU, 48940 Leioa, Bizkaia, Spain.ORCID 0000-0002-4087-8729
University of the Basque Country · ESInstituto Biofisika · ESHospital de Basurto · ESIkerbasque · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and, followed by a cascade of events (accumulation of lipids, fibrous elements, and calcification), triggers the vessel narrowing and activation of inflammatory pathways. The resultant atheroma plaque, along with these processes, results in cardiovascular complications. This review focuses on the different stages of atherosclerosis development, ranging from endothelial dysfunction to plaque rupture. In addition, the post-transcriptional regulation and modulation of atheroma plaque by microRNAs and lncRNAs, the role of microbiota, and the importance of sex as a crucial risk factor in atherosclerosis are covered here in order to provide a global view of the disease.

Indexed as

AtherosclerosisCalcinosisCardiovascular DiseasesPlaque, AtheroscleroticHumansRisk Factorsatheroma plaqueatherosclerosisendothelial dysfunctionlncRNAmicrobiotamicroRNAocLDLrisk factors

Identifiers

PMID35328769
PMCPMC8954705
OpenAlexW4220799853

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.