SynthesisInternational journal of environmental research and public health2022
Risk Factors for Brain Health in Agricultural Work: A Systematic Review.
Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Prevalence of Anxiety Symptoms by Sociodemographic and Employment Characteristics in a National Sample of Hired Crop Workers: Evidence From the National Agricultural Workers Survey (2018-2022).American journal of industrial medicine · 2026Article
- Current status of neurotrauma management in resource-limited settings.Annals of medicine and surgery (2012) · 2025Review
- Leveraging Administrative Health Databases to Address Health Challenges in Farming Populations: Scoping Review and Bibliometric Analysis (1975-2024).JMIR public health and surveillance · 2025Article
- Investigating Parkinson's disease risk across farming activities using data mining and large-scale administrative health data.NPJ Parkinson's disease · 2025Article
- Air Pollution as an Environmental Risk Factor for Alzheimer's Disease and Related Dementias.Medical research archives · 2024Article
- Machine learning and XAI approaches highlight the strong connection betweenScientific reports · 2024Article
- Agricultural activities and risk of Alzheimer's disease: the TRACTOR project, a nationwide retrospective cohort study.European journal of epidemiology · 2024Article
- Multiple Sclerosis: New Insights into Molecular Pathogenesis and Novel Platforms for Disease Treatment.Current drug research reviews · 2024Review
- Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Certain exposures related to agricultural work have been associated with neurological disorders. To date, few studies have included brain health measurements to link specific risk factors with possible neural mechanisms. Moreover, a synthesis of agricultural risk factors associated with poorer brain health outcomes is missing. In this systematic review, we identified 106 articles using keywords related to agriculture, occupational exposure, and the brain. We identified seven major risk factors: non-specific factors that are associated with agricultural work itself, toluene, pesticides, heavy metal or dust exposure, work with farm animals, and nicotine exposure from plants. Of these, pesticides are the most highly studied. The majority of qualifying studies were epidemiological studies. Nigral striatal regions were the most well studied brain area impacted. Of the three human neuroimaging studies we found, two focused on functional networks and the third focused on gray matter. We identified two major directions for future studies that will help inform preventative strategies for brain health in vulnerable agricultural workers: (1) the effects of moderators such as type of work, sex, migrant status, race, and age; and (2) more comprehensive brain imaging studies, both observational and experimental, involving several imaging techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.