SynthesisInternational journal of environmental research and public health2022
Exposure to Antineoplastic Drugs in Occupational Settings: A Systematic Review of Biological Monitoring Data.
Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Cancer risks of hematopoietic/lymphatic and urinary system in pharmaceutical plant workers: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Comparative analysis of dermal and inhalation exposures to antineoplastic drugs among workers in the workplaces: a systematic review.BMC public health · 2025Pooled it
- Exposure Assessment and Monitoring of Antiblastic Drugs Preparation in Health Care Settings: A Systematic Review.La Medicina del lavoro · 2024Pooled it
- Occupational Reproductive Health Risks Among Women Healthcare Workers: A Narrative Review for Clinical Surveillance, Preconception Counseling, and Prevention.Journal of clinical medicine · 2026Review
- Development and Validation of the Health Belief Model-Based Occupational Exposure Risk Perception Scale for Nursing Staff.Journal of nursing management · 2026Article
- Factors Influencing the Use of Personal Protective Equipment in the Handling of Chemotherapy Drugs Among Nursing Staff in Cancer Hospitals: A Cross-Sectional Study.Journal of nursing management · 2026Article
- Cuproptosis in lung cancer: a nexus of ncRNA regulation, epigenetics, and tumor microenvironment Remodeling.Clinical and experimental medicine · 2025Review
- Artificial Intelligence-Driven Strategies for Targeted Delivery and Enhanced Stability of RNA-Based Lipid Nanoparticle Cancer Vaccines.Pharmaceutics · 2025Review
- Gloves Standards and Occupational Exposure to Antineoplastic Drugs in the European Context.Health science reports · 2025Article
- Application of a multifunctional chemotherapy infusion device for reducing antineoplastic drug extravasation.Frontiers in oncology · 2025Article
- lncRNAs as prognostic markers and therapeutic targets in cuproptosis-mediated cancer.Clinical and experimental medicine · 2024Review
- An Automated Micro Solid-Phase Extraction (μSPE) Liquid Chromatography-Mass Spectrometry Method for Cyclophosphamide and Iphosphamide: Biological Monitoring in Antineoplastic Drug (AD) Occupational Exposure.Molecules (Basel, Switzerland) · 2024Article
- Psychometric properties of the Chinese version of the oncology nurses health behaviors determinants scale: a cross-sectional study.Frontiers in public health · 2024Article
- Evaluation of the risk of occupational exposure to antineoplastic drugs in healthcare sector: part I - medical gloves.Arhiv za higijenu rada i toksikologiju · 2023Article
- Article
- Occupational Exposure to Antineoplastic Drugs in Twelve French Health Care Setting: Biological Monitoring and Surface Contamination.International journal of environmental research and public health · 2023Article
- Reporting environmental contamination results to healthcare workers could play a crucial role in decreasing the risk of occupational exposure to antineoplastic drugs.Frontiers in public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The high toxicity of antineoplastic drugs (ADs) makes them dangerous not only for patients, but also for exposed workers. Therefore, the aim of this review was to provide an updated overview of the biological monitoring of occupational AD exposure in order to extrapolate information useful to improve risk assessment and management strategies in workplaces. Several studies demonstrated that remarkable portions of healthcare workers may have traces of these substances or their metabolites in biological fluids, although with some conflicting results. Nurses, directly engaged in AD handling, were the occupational category at higher risk of contamination, although, in some cases, personnel not involved in AD-related tasks also showed quantifiable internal doses. Overall, further research carried out on greater sample sizes appears necessary to gain deeper insight into the variability retrieved in the reported results. This may be important to understand the impact of the extent of ADs use, different handling, procedures, and cleaning practices, spill occurrence, training of the workforce, as well as the adoption of adequate collective and personal protective equipment in affecting the occupational exposure levels. This may support the achievement of the greatest clinical efficiency of such therapies while assuring the health and safety of involved workers.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.