Evidence map›Paper›PMID 35332236›Full record

ArticleScientific reports2022

Fractal analysis of 4D dynamic myocardial stress-CT perfusion imaging differentiates micro- and macrovascular ischemia in a multi-center proof-of-concept study.

Florian Michallek, Satoshi Nakamura, Hideki Ota, Ryo Ogawa, Takehito Shizuka, Hitoshi Nakashima, Yi-Ning Wang, Tatsuro Ito, Hajime Sakuma, Marc Dewey and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Florian MichallekDepartment of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany. florian.michallek@charite.de.
Satoshi NakamuraDepartment of Radiology, Mie University Graduate School of Medicine, Mie, Japan.
Hideki OtaDepartment of Advanced MRI Collaborative Research, Tohoku University Graduate School of Medicine, Miyagi, Japan.
Ryo OgawaSaiseikai Matsuyama Hospital, Matsuyama, Japan.
Takehito ShizukaTakasaki General Medical Center, Takasaki, Japan.
Hitoshi NakashimaNational Hospital Organization Kagoshima Medical Center, Kagoshima, Japan.
Yi-Ning WangPeking Union Medical College Hospital, Beijing, China.
Tatsuro ItoKobe University Graduate School of Medicine, Kobe, Japan.
Hajime SakumaDepartment of Radiology, Mie University Graduate School of Medicine, Mie, Japan.
Marc Dewey *Department of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany. marc.dewey@charite.de.
Kakuya Kitagawa *Department of Advanced Diagnostic Imaging, Mie University Graduate School of Medicine, Mie, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fractal analysis of dynamic, four-dimensional computed tomography myocardial perfusion (4D-CTP) imaging might have potential for noninvasive differentiation of microvascular ischemia and macrovascular coronary artery disease (CAD) using fractal dimension (FD) as quantitative parameter for perfusion complexity. This multi-center proof-of-concept study included 30 rigorously characterized patients from the AMPLIFiED trial with nonoverlapping and confirmed microvascular ischemia (n

Indexed as

Coronary Artery DiseaseFractional Flow Reserve, MyocardialMyocardial Perfusion ImagingComputed Tomography AngiographyCoronary AngiographyFractalsHumansIschemiaPredictive Value of Tests

Identifiers

PMID35332236
PMCPMC8948301

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.