ArticleEnvironmental health perspectives2022
Biomarkers of Exposure to Phthalate Mixtures and Adverse Birth Outcomes in a Puerto Rico Birth Cohort.
Article in Environmental health perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- Endocrine Disruptors at the Fetomaternal Interface: Insight From PBDE Studies and the Utility of Novel Approach Methods.Endocrinology · 2026Review
- The associations between mixed blood heavy metal exposure and depressive symptom: a cross-sectional study in Shandong, China.BMC public health · 2025Article
- Article
- Improving the Health and Environmental Health Literacy of Professionals: Evaluating the Effect of a Virtual Intervention on Phthalate Environmental Health Literacy.International journal of environmental research and public health · 2024Article
- Metabolomic Alterations Associated with Phthalate Exposures among Pregnant Women in Puerto Rico.Environmental science & technology · 2024Article
- Endocrine Disruptors in Pregnancy: Effects on Mothers and Fetuses-A Review.Journal of clinical medicine · 2024Review
- Potential mechanisms and modifications of dietary antioxidants on the associations between co-exposure to plastic additives and diabetes.Nutrition & diabetes · 2024Article
- Associations between urinary hydroxylated polycyclic aromatic hydrocarbon biomarker concentrations and measures of timing of delivery and infant size at birth.Environment international · 2024Article
- Associations of maternal blood metal concentrations with plasma eicosanoids among pregnant women in Puerto Rico.The Science of the total environment · 2024Article
- Urinary concentrations of phthalate metabolites in relation to preeclampsia and other hypertensive disorders of pregnancy in the environmental influences on child health outcomes (ECHO) program.Environment international · 2024Article
- Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort.Journal of neurology, neurosurgery, and psychiatry · 2024Article
- Prenatal phthalate exposure and adverse birth outcomes in the USA: a prospective analysis of births and estimates of attributable burden and costs.The Lancet. Planetary health · 2024Article
- Association of chronic cough with exposure to polycyclic aromatic hydrocarbons in the US population.Heliyon · 2024Article
- Prenatal Exposure to Heavy Metals and Adverse Birth Outcomes: Evidence From an E-Waste Area in China.GeoHealth · 2023Article
- Associations of phthalates, phthalate replacements, and their mixtures with eicosanoid biomarkers during pregnancy.Environment international · 2023Article
- Early pregnancy phthalates and replacements in relation to fetal growth: The human placenta and phthalates study.Environmental research · 2023Article
- Evaluating Chemical Mixtures in Epidemiological Studies to Inform Regulatory Decisions.Environmental health perspectives · 2023Article
- Mono(2-ethylhexyl) phthalate induces transcriptomic changes in placental cells based on concentration, fetal sex, and trophoblast cell type.Archives of toxicology · 2023Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundHumans are exposed to complex mixtures of phthalate chemicals from a range of consumer products. Previous studies have reported significant associations between individual phthalate metabolites and pregnancy outcomes, but mixtures research is limited.
objectivesWe used the Puerto Rico Testsite for Exploring Contamination Threats longitudinal pregnancy cohort to investigate associations between phthalate metabolite mixtures and pregnancy outcomes.
methodsWomen (
resultsDifferences in metabolite weights from ridge and elastic net were apparent between birth outcomes and between fetal sexes. An interquartile range increase in gestational average phthalate ERS was associated with increased odds of PTB [male DISCUSSION: These results suggest that exposure to phthalate mixtures was associated with increased risk of early delivery and highlight the need to study mixtures by fetal sex. We also identified various metabolites displaying nonlinear relationships with measures of birth weight. https://doi.org/10.1289/EHP8990.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.