Evidence map›Paper›PMID 35336782›Full record

ArticleBiology2022

Immuno-PET Imaging of Atherosclerotic Plaques with [

Kikkie Poels, Maxime Schreurs, Matthijs Jansen, Danielle J Vugts, Tom T P Seijkens, Guus A M S van Dongen, Esther Lutgens, Wissam Beaino

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Immuno-positron emission tomography in cardiovascular disease: Advances, challenges, and opportunities.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2026
    Review
  2. Can Nuclear Imaging Detect Trained Immunity in Cardiovascular Disease?Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  3. A scoping review on potential of novel developments in fever of unknown origin and inflammation of unknown origin: long-axial-field-of-view positron emission tomography/computed tomography and novel radiotracers.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2025
    Article
  4. Targeted drug delivery systems for atherosclerosis.Journal of nanobiotechnology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kikkie PoelsDepartment of Medical Biochemistry, Amsterdam Cardiovascular Sciences (ACS), Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-6156-2336
Maxime SchreursDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Unversiteit, 1081 HV Amsterdam, The Netherlands.
Matthijs JansenDepartment of Medical Biochemistry, Amsterdam Cardiovascular Sciences (ACS), Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Danielle J VugtsDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Unversiteit, 1081 HV Amsterdam, The Netherlands.
Tom T P SeijkensDepartment of Medical Biochemistry, Amsterdam Cardiovascular Sciences (ACS), Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Guus A M S van DongenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Unversiteit, 1081 HV Amsterdam, The Netherlands.
Esther LutgensDepartment of Medical Biochemistry, Amsterdam Cardiovascular Sciences (ACS), Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Wissam BeainoDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Unversiteit, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0003-2216-4439
Amsterdam University Medical Centers · NLGerman Centre for Cardiovascular Research · DEThe Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-invasive imaging of atherosclerosis can help in the identification of vulnerable plaque lesions. CD40 is a co-stimulatory molecule present on various immune and non-immune cells in the plaques and is linked to inflammation and plaque instability. We hypothesize that a

Indexed as

89Zr-immuno-PETatherosclerotic plaquescardiovascular diseaseCD40 imagingex vivo biodistributionmacrophagesPET-CT

Identifiers

PMID35336782
PMCPMC8944956
OpenAlexW4220942101

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.