Evidence map›Paper›PMID 35343269›Full record

Trial reportJournal of diabetes science and technology2023

Long-term Continuous Glucose Monitor Use in Very Young Children With Type 1 Diabetes: One-Year Results From the SENCE Study.

Michelle A Van Name, Lauren G Kanapka, Linda A DiMeglio, Kellee M Miller, Anastasia Albanese-O'Neill, Persis Commissariat, Sarah D Corathers, Kara R Harrington, Marisa E Hilliard, Barbara J Anderson and 12 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of diabetes science and technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 15 institutions in 1 country.

Michelle A Van NameYale School of Medicine, New Haven, CT, USA.
Lauren G KanapkaJaeb Center for Health Research, Tampa, FL, USA.
Linda A DiMeglioRiley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN, USA.ORCID 0000-0003-4440-5168
Kellee M MillerJaeb Center for Health Research, Tampa, FL, USA.
Anastasia Albanese-O'NeillDepartment of Pediatrics, University of Florida, Gainesville, FL, USA.ORCID 0000-0001-8219-6059
Persis CommissariatJoslin Diabetes Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-6964-1223
Sarah D CorathersCincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.
Kara R HarringtonJoslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Marisa E HilliardTexas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Barbara J AndersonTexas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Jennifer C KelleyVanderbilt University Medical Center, Nashville, TN, USA.
Lori M LaffelJoslin Diabetes Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-9675-3001
Sarah A MacLeishRainbow Babies and Children's Hospital, Cleveland, OH, USA.
Brandon M NathanUniversity of Minnesota, Minneapolis, MN, USA.
William V TamborlaneYale School of Medicine, New Haven, CT, USA.
R Paul WadwaBarbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Steven M WilliChildren's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kristen M WilliamsNaomi Berrie Diabetes Center, Columbia University, New York, NY, USA.ORCID 0000-0002-8464-4537
Kupper A WintergerstWendy Novak Diabetes Center, University of Louisville, Norton Children's Hospital, Louisville, KY, USA.
Stephanie WoernerRiley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN, USA.
Jenise C WongMadison Clinic for Pediatric Diabetes, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-0573-6650
Daniel J DeSalvoTexas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine · USJoslin Diabetes Center · USJaeb Center for Health Research · USRiley Hospital for Children · USYale University · USChildren's Hospital of Philadelphia · USCincinnati Children's Hospital Medical Center · USColumbia University · USRainbow Babies & Children's Hospital · USUniversity of California, San Francisco · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Florida · USUniversity of Louisville · USUniversity of Minnesota · USVanderbilt University Medical Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI GERALD I SHULMAN · 1993 to 2026
$44.0M
NCATS NIH HHS UL1 TR001863NIDDK NIH HHS P30 DK036836NIDDK NIH HHS P30 DK045735
6 · The paper itself

Abstract

objectivesAchieving optimal glycemic outcomes in young children with type 1 diabetes (T1D) is challenging. This study examined the durability of continuous glucose monitoring (CGM) coupled with a family behavioral intervention (FBI) to improve glycemia. STUDY

designThis one-year study included an initial 26-week randomized controlled trial of CGM with FBI (

resultsTime in range (70-180 mg/dL) did not improve with CGM use (CGM+FBI: baseline 37%, 52 weeks 41%; Standard-CGM: baseline 41%, 52 weeks 44%; BGM-Crossover: 26 weeks 38%, 52 weeks 40%). All three groups sustained decreases in hypoglycemia (<70 mg/dL) with CGM use (CGM+FBI: baseline 3.4%, 52 weeks 2.0%; Standard-CGM: baseline 4.1%, 52 weeks 2.1%; BGM-Crossover: 26 weeks 4.5%, 52 weeks 1.7%,

conclusionOver 12 months young children with T1D using newer CGM technology sustained reductions in hypoglycemia and, in contrast to prior studies, persistently wore CGM. However, pervasive hyperglycemia remained unmitigated. This indicates an urgent need for further advances in diabetes technology, behavioral support, and diabetes management educational approaches to optimize glycemia in young children.

Indexed as

Diabetes Mellitus, Type 1HyperglycemiaHypoglycemiaBlood GlucoseBlood Glucose Self-MonitoringChildChild, PreschoolHumansBlood Glucosebehavioral interventioncontinuous glucose monitoringglycemic controlhypoglycemiayoung children

Identifiers

PMID35343269
PMCPMC10348002
OpenAlexW4220990420

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.