Evidence map›Paper›PMID 35345544›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2022

Relationship Between Thyroid Hormone and Liver Steatosis Analysis Parameter in Obese Participants: A Case-Control Study.

Shuqin Chen, Yong Jin, Miao Xu, Pingping Zhang, Ye Zhou, Xingjun Qian, Qifa Song, Shizhong Bu, Jing Sun, Li Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Shuqin Chen *Department of Endocrinology and Metabolism, Ningbo First Hospital, Ningbo, Zhejiang Province, People's Republic of China.ORCID 0000-0002-6654-4938
Yong Jin *Department of Internal Medicine, Ningbo Yinzhou Second Hospital, Ningbo, Zhejiang Province, People's Republic of China.
Miao XuDepartment of Endocrinology and Metabolism, Ningbo First Hospital, Ningbo, Zhejiang Province, People's Republic of China.ORCID 0000-0003-2411-9295
Pingping ZhangSchool of Public Health, Peking University, Beijing, People's Republic of China.
Ye ZhouDepartment of Endocrinology and Metabolism, Ningbo First Hospital, Ningbo, Zhejiang Province, People's Republic of China.ORCID 0000-0002-1576-069X
Xingjun QianHealth Management Center, Ningbo First Hospital, Ningbo, Zhejiang Province, People's Republic of China.
Qifa SongMedical Research Center, Ningbo First Hospital, Ningbo, Zhejiang Province, People's Republic of China.ORCID 0000-0001-9753-2924
Shizhong BuDiabetes Research Center, School of Medicine, Ningbo University, Ningbo, Zhejiang Province, People's Republic of China.
Jing SunSchool of Medicine and Dentistry, Griffith University, Gold Coast, Queensland, Australia.ORCID 0000-0002-0097-2438
Li LiDepartment of Endocrinology and Metabolism, Ningbo First Hospital, Ningbo, Zhejiang Province, People's Republic of China.ORCID 0000-0001-6301-3544
Ningbo First Hospital · CNGriffith University · AUNingbo No. 2 Hospital · CNNingbo University · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The thyroid hormone has been demonstrated to be associated with nonalcoholic fatty liver disease (NAFLD) in different populations. However, the relationship between thyroid hormone and the degree of liver steatosis in overweight/obese subjects is still unclear. Liver ultra-sound attenuation (LiSA) is a newly developed ultrasound attenuation parameter for the analysis of hepatic steatosis. The study aimed to characterize the relationship between thyroid hormone and LiSA in overweight/obese participants. Methods: This case-control study was performed in Ningbo First Hospital, China. A total of 24 lean, 66 overweight and 49 obese participants were consecutively recruited from January 2021 to May 2021. Thyroid hormone and other clinical features were measured. LiSA was acquired by using a Hepatus ultrasound machine. Multiple linear regression analyses were performed to examine associations of LiSA and clinic indices. Results: Obese subjects had higher LiSA, fT3 and TSH levels than lean participants of similar age and sex ( Conclusion: The fT3 level was independently associated with the degree of liver steatosis among the overweight/obese participants.

Indexed as

LiSANAFLDobesitythyroid hormone

Identifiers

PMID35345544
PMCPMC8957298
OpenAlexW4226156555

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.