Evidence map›Paper›PMID 35347084›Full record

ArticleAging2022

VEGF-A-related genetic variants protect against Alzheimer's disease.

Alexandros M Petrelis, Maria G Stathopoulou, Maria Kafyra, Helena Murray, Christine Masson, John Lamont, Peter Fitzgerald, George Dedoussis, Frances T Yen, Sophie Visvikis-Siest

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Alexandros M PetrelisIGE-PCV, Université de Lorraine, Nancy 54000, France.
Maria G StathopoulouInserm, C3M, Team Control of Gene Expression (10), Université Cote d'Azur, Nice, France.
Maria KafyraIGE-PCV, Université de Lorraine, Nancy 54000, France.
Helena MurrayRandox Laboratories Limited, Crumlin, County Antrim BT29 4QY, United Kingdom.
Christine MassonIGE-PCV, Université de Lorraine, Nancy 54000, France.
John LamontRandox Laboratories Limited, Crumlin, County Antrim BT29 4QY, United Kingdom.
Peter FitzgeraldRandox Laboratories Limited, Crumlin, County Antrim BT29 4QY, United Kingdom.
George DedoussisIGE-PCV, Université de Lorraine, Nancy 54000, France.
Frances T YenQualivie, UR AFPA laboratory, University of Lorraine, Vandoeuvre-les-Nancy, Lorraine, France.
Sophie Visvikis-SiestIGE-PCV, Université de Lorraine, Nancy 54000, France.
Interactions Gène-Environnement en Physiopathologie Cardio-Vasculaire · FRRandox (United Kingdom) · GBHarokopio University of Athens · GRInserm · FRLaboratoire Animal et Agroécosystèmes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Apolipoprotein E (

Indexed as

Alzheimer DiseaseVascular Endothelial Growth Factor AAllelesApolipoproteins EGenetic Predisposition to DiseaseGenome-Wide Association StudyGenotypeHumansPolymorphism, Single NucleotideApoE protein, humanApolipoproteins EVascular Endothelial Growth Factor AVEGFA protein, humanAlzheimer’s diseaseApolipoprotein Eelastic netepistasisLSRmachine learningpredictionVEGF-A

Identifiers

PMID35347084
PMCPMC9004571
OpenAlexW4220763459

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.