SynthesisNature medicine2022
Suicide risk and mortality among patients with cancer.
Synthesis in Nature medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07409584 (Mental Health and Suicidality in Glioblastoma Patients in Germany - a Multicenter Observational Study), which is not on this map. Cited by 74 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mental Health and Suicidality in Glioblastoma Patients in Germany - a Multicenter Observational Study (SHINE-GLIO Study)
Who cites it
74 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of renal cell carcinoma, version 3.0.Journal for immunotherapy of cancer · 2026Guideline
- Ketamine treatment alleviates suicide ideation in high-risk populations: a systematic review and meta-analysis.Epidemiology and psychiatric sciences · 2026Pooled it
- Suicide risk and mortality among patients with cancers of the digestive system: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Psychological Distress in Bladder Cancer Patients: A Systematic Review.Cancer medicine · 2024Pooled it
- Individual-level risk factors for suicide mortality in the general population: an umbrella review.The Lancet. Public health · 2023Pooled it
- Suicide Mortality Risk among Patients with Lung Cancer-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- The Efficacy of Reminiscence Therapy in Cancer-Related Symptom Management: A Systematic Review and Meta-Analysis.Integrative cancer therapiesPooled it
- Mental health and suicidality in glioblastoma patients in germany - a multicenter cross-sectional observational study protocol (SHINE-GLIO Study).Neurological research and practice · 2026Article
- Suicide among patients with cancer: a retrospective study of medical treatment-related factors associated with suicide.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Global Qualitative Study of Professionals' Perspectives of Caring for People With Head and Neck Cancer Experiencing Suicidal Ideation.Psycho-oncology · 2026Article
- Metabolic Crosstalk Between Host and Tumor as a Circuit of Resilience in Cancer Therapy.Cells · 2026Review
- Association between prostate cancer and mental health: a comparison across cancer types using the medical expenditure panel survey, 2017-2022.Journal of cancer survivorship : research and practice · 2026Article
- Methods of Suicide Used by People With Cancer: A Scoping Review.Psycho-oncology · 2026Article
- Suicide Rates Among Patients Receiving Palliative Care-Descriptive Results of a National Cohort Study.Journal of clinical medicine · 2026Article
- Association of GnRH agonists with depression and suicide/self-injury: a FAERS pharmacovigilance study.Endocrine connections · 2026Article
- Article
- Long-term survival and successful pregnancy in a Nigerian woman with concurrent diagnosis of non-Hodgkin lymphoma and chronic myeloid leukemia: a case report.Journal of medical case reports · 2026Article
- Suicide prevention in Japanese cancer care hospitals: a topic modeling analysis of manuals and workflows.Frontiers in psychiatry · 2026Article
- Mapping the genetic landscape of suicide risk: Insights from genomic SEM.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Article
- Developing and validating a nomogram of suicide risk in lung cancer patients based on the SEER database.Discover oncology · 2025Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
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- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite substantial progress in cancer therapy in recent decades, patients with cancer remain at high suicide risk. Data from individual studies have not been comprehensively quantified and specific risk factors are ill-defined. We assessed suicide mortality risk according to cancer prognosis, stage, time since diagnosis, gender, ethnicity, marital status, year of recruitment and geographic region. We searched EMBASE, MEDLINE, PsycINFO, Web of Science, CINAHL and Google Scholar for relevant articles up to February 2021. We used a random effects model, performed meta-regression meta-analysis and assessed heterogeneity and publication bias using I², funnel plots and Egger's and Begg's tests. We performed a systematic review including 62 studies and 46,952,813 patients. To avoid patient sample overlap, the meta-analysis was performed on 28 studies, involving 22,407,690 patients with cancer. Suicide mortality was significantly increased compared with the general population (standardized mortality ratio = 1.85, 95% confidence interval = 1.55-2.20). Risk was strongly related to cancer prognosis, cancer stage, time since diagnosis and geographic region. Patients with cancer, particularly those with specific risk factors, should be closely monitored for suicidality and need specialized care to reduce short- and long-term risks of suicide.
Indexed as
Identifiers
35347279What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.