Evidence map›Paper›PMID 35348295›Full record

ArticleJournal of diabetes investigation2022

Association between maternal gestational diabetes mellitus and high-sensitivity C-reactive protein levels in 8-year-old children: The Yamanashi Adjunct Study of the Japan Environment and Children's Study (JECS).

Tetsuo Sekine, Kyoichiro Tsuchiya, Hiroyuki Uchinuma, Sayaka Horiuchi, Megumi Kushima, Sanae Otawa, Hiroshi Yokomichi, Kunio Miyake, Yuka Akiyama, Tadao Ooka and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Tetsuo SekineInterdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo City, Japan.
Kyoichiro TsuchiyaInterdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo City, Japan.ORCID https://orcid.org/0000-0002-2863-4561
Hiroyuki UchinumaInterdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo City, Japan.
Sayaka HoriuchiCenter for Birth Cohort Studies, University of Yamanashi, Chuo City, Japan.
Megumi KushimaCenter for Birth Cohort Studies, University of Yamanashi, Chuo City, Japan.
Sanae OtawaCenter for Birth Cohort Studies, University of Yamanashi, Chuo City, Japan.
Hiroshi YokomichiDepartment of Health Sciences, School of Medicine, University of Yamanashi, Chuo City, Japan.ORCID https://orcid.org/0000-0001-7369-155X
Kunio MiyakeDepartment of Health Sciences, School of Medicine, University of Yamanashi, Chuo City, Japan.
Yuka AkiyamaDepartment of Health Sciences, School of Medicine, University of Yamanashi, Chuo City, Japan.
Tadao OokaDepartment of Health Sciences, School of Medicine, University of Yamanashi, Chuo City, Japan.
Reiji KojimaDepartment of Health Sciences, School of Medicine, University of Yamanashi, Chuo City, Japan.
Ryoji ShinoharaCenter for Birth Cohort Studies, University of Yamanashi, Chuo City, Japan.
Zentaro YamagataCenter for Birth Cohort Studies, University of Yamanashi, Chuo City, Japan.
Yamanashi Adjunct Study of the Japan Environment, Children’s Study Group
University of Yamanashi Hospital · JPUniversity of Yamanashi · JP

Funding

Ministry of the Environment, Japan
6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) is one of the most common pregnancy-related complications; it is associated with adverse pregnancy outcomes and metabolic disorders in offspring, consistent with the concept of the developmental origins of health and disease. This cohort study of women without diabetes (n = 761), who were part of the Yamanashi Adjunct Study of the Japan Environment and Children's Study, aimed to explore the associations between maternal GDM and their offspring's level of high-sensitivity C-reactive protein (hsCRP), a biomarker of inflammatory and cardiovascular diseases. We analyzed the associations between GDM and the offspring's hsCRP levels using a multiple logistic regression model. A mother with GDM significantly increased the risk for high hsCRP level by 4.07-fold (≥2.0 mg/L) in the child. As such, maternal GDM was significantly associated with increased serum hsCRP levels in 8-year-old children.

Indexed as

Diabetes, GestationalPregnancy ComplicationsChildCohort StudiesC-Reactive ProteinFemaleHumansJapanPregnancyRisk FactorsC-Reactive ProteinCohort studyMetabolic syndromeObesity

Identifiers

PMID35348295
PMCPMC9340882
OpenAlexW4220992568

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.