Evidence map›Paper›PMID 35352014›Full record

Trial reportEuropean journal of clinical nutrition2022

No effect of nitrate-rich beetroot juice on microvascular function and blood pressure in younger and older individuals: a randomised, placebo-controlled double-blind pilot study.

David Rogerson, Fabio Alejandro Aguilar Mora, Jamie Stuart Young, Markos Klonizakis

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Nitric Oxide Signaling and Sensing in Age-Related Diseases.Antioxidants (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

David RogersonSport and Physical Activity Research Centre, Department of Sport and Physical Activity, Sheffield Hallam University, Sheffield, UK.
Fabio Alejandro Aguilar MoraLifestyle, Exercise and Nutrition Improvement (LENI) Research Group, Department of Nursing and Midwifery, Faculty of Health and Wellbeing, Sheffield Hallam University, Sheffield, UK.
Jamie Stuart YoungBiomolecular Sciences Research Centre, Sheffield Hallam University, Sheffield, UK.
Markos KlonizakisLifestyle, Exercise and Nutrition Improvement (LENI) Research Group, Department of Nursing and Midwifery, Faculty of Health and Wellbeing, Sheffield Hallam University, Sheffield, UK. M.Klonizakis@shu.ac.uk.ORCID 0000-0002-8864-4403
Sheffield Hallam University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesTo compare the effects of supplemental inorganic nitrate (NO SUBJECTS/

methods25 individuals participated in a double-blind, randomised, placebo-controlled crossover pilot study. Participants were stratified by age (18-35 and ≥55 years) and consumed a single dose beetroot juice (providing 6.4 mmol NO

resultsTreatments and methods were well tolerated, and no adverse events were reported. Urinary NO

conclusionsBeetroot juice had no effect on blood pressure or microvascular endothelial function in young and older individuals. Dosage and timing regimens for supplemental beetroot juice should be avenues for further inquiry.

Indexed as

Beta vulgarisNitratesAntioxidantsBlood PressureCross-Over StudiesDietary SupplementsDouble-Blind MethodFruit and Vegetable JuicesHumansMicrocirculationMiddle AgedNitritesPilot ProjectsAntioxidantsNitratesNitrites

Identifiers

PMID35352014
PMCPMC9550618
OpenAlexW4220749063

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.