Evidence map›Paper›PMID 35354491›Full record

ArticleMobile DNA2022

A beginner's guide to manual curation of transposable elements.

Clement Goubert, Rory J Craig, Agustin F Bilat, Valentina Peona, Aaron A Vogan, Anna V Protasio

Erratum issuedAbstract read
In one paragraph

Article in Mobile DNA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 100 papers.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed.

  1. Near-complete genomes for nine haplochromine cichlid fishes reveal a novel centromeric satellite structure organised around a pair of inverted elements.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
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  19. Genome-wide in-silico identification and characterization of LTR retrotransposons in domestic goat (Capra hircus).Mammalian genome : official journal of the International Mammalian Genome Society · 2026
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Clement GoubertCanadian Center for Computational Genomics, McGill University, Montreal, Québec, Canada.
Rory J CraigInstitute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 3FL, UK.
Agustin F BilatDepartamento de Genética, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.
Valentina PeonaDepartment of Organismal Biology, Uppsala University, Norbyvägen 18D, 752 36, Uppsala, Sweden.
Aaron A VoganDepartment of Organismal Biology, Uppsala University, Norbyvägen 18D, 752 36, Uppsala, Sweden.
Anna V ProtasioDepartment of Pathology, Tennis Court Road, Cambridge, CB1 2PQ, UK. avp25@cam.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the study of transposable elements (TEs), the generation of a high confidence set of consensus sequences that represent the diversity of TEs found in a given genome is a key step in the path to investigate these fascinating genomic elements. Many algorithms and pipelines are available to automatically identify putative TE families present in a genome. Despite the availability of these valuable resources, producing a library of high-quality full-length TE consensus sequences largely remains a process of manual curation. This know-how is often passed on from mentor-to-mentee within research groups, making it difficult for those outside the field to access this highly specialised skill.

resultsOur manuscript attempts to fill this gap by providing a set of detailed computer protocols, software recommendations and video tutorials for those aiming to manually curate TEs. Detailed step-by-step protocols, aimed at the complete beginner, are presented in the Supplementary Methods.

conclusionsThe proposed set of programs and tools presented here will make the process of manual curation achievable and amenable to all researchers and in special to those new to the field of TEs.

Identifiers

PMID35354491
PMCPMC8969392

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.