Evidence map›Paper›PMID 35354608›Full record

ArticleGenome research2022

The role of insulators and transcription in 3D chromatin organization of flies.

Keerthi T Chathoth, Liudmila A Mikheeva, Gilles Crevel, Jareth C Wolfe, Ioni Hunter, Saskia Beckett-Doyle, Sue Cotterill, Hongsheng Dai, Andrew Harrison, Nicolae Radu Zabet

Open access · hybridAbstract read
In one paragraph

Article in Genome research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Article
  7. ThebioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Set2 and H3K36 regulate thebioRxiv : the preprint server for biology · 2024
    Article
  13. Multiple Roles of dXNP and dADD1-International journal of molecular sciences · 2023
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Keerthi T Chathoth *School of Life Sciences, University of Essex, Colchester CO4 3SQ, United Kingdom.
Liudmila A Mikheeva *School of Life Sciences, University of Essex, Colchester CO4 3SQ, United Kingdom.
Gilles CrevelDepartment Basic Medical Sciences, St. Georges University London, London SW17 0RE, United Kingdom.
Jareth C WolfeSchool of Life Sciences, University of Essex, Colchester CO4 3SQ, United Kingdom.
Ioni HunterSchool of Life Sciences, University of Essex, Colchester CO4 3SQ, United Kingdom.
Saskia Beckett-DoyleSchool of Life Sciences, University of Essex, Colchester CO4 3SQ, United Kingdom.
Sue CotterillDepartment Basic Medical Sciences, St. Georges University London, London SW17 0RE, United Kingdom.
Hongsheng DaiDepartment of Mathematical Sciences, University of Essex, Colchester CO4 3SQ, United Kingdom.
Andrew HarrisonDepartment of Mathematical Sciences, University of Essex, Colchester CO4 3SQ, United Kingdom.
Nicolae Radu ZabetSchool of Life Sciences, University of Essex, Colchester CO4 3SQ, United Kingdom.ORCID 0000-0001-9964-6271
University of Essex · GBSt George's, University of London · GB

Funding

Wellcome TrustWellcome Trust 202012/Z/16/Z
6 · The paper itself

Abstract

The DNA in many organisms, including humans, is shown to be organized in topologically associating domains (TADs). In

Indexed as

ChromatinDrosophila ProteinsAnimalsChromosomesDNA-Binding ProteinsDrosophilaDrosophila melanogasterEye ProteinsMicrotubule-Associated ProteinsNuclear ProteinsTranscription FactorsBEAF-32 protein, DrosophilaChromatinCP190 protein, DrosophilaDNA-Binding ProteinsDref protein, DrosophilaDrosophila ProteinsEye ProteinsMicrotubule-Associated ProteinsNuclear ProteinsTranscription Factors

Identifiers

PMID35354608
PMCPMC8997359
OpenAlexW4221002005

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.