Evidence map›Paper›PMID 35357670›Full record

ReviewJournal of cardiovascular translational research2022

The Role of Angiogenesis and Arteriogenesis in Myocardial Infarction and Coronary Revascularization.

Cristiano Spadaccio, Antonio Nenna, David Rose, Francesco Piccirillo, Annunziata Nusca, Francesco Grigioni, Massimo Chello, Gus J Vlahakes

Erratum issuedOpen access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cardiovascular translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Engineering Nanoparticles and Bioscaffolds for Targeted microRNA Delivery in Cardiovascular Regeneration-A Comprehensive Review.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Year in Review 2023: Noteworthy Literature in Cardiac Anesthesiology.Seminars in cardiothoracic and vascular anesthesia · 2024
    Review
  15. Article
  16. Tenascin-C in Tissue Repair after Myocardial Infarction in Humans.International journal of molecular sciences · 2023
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Cristiano SpadaccioCardiac Surgery, Massachusetts General Hospital & Harvard Medical School, Boston, USA. cristianospadaccio@gmail.com.ORCID 0000-0002-1672-7576
Antonio NennaCardiac Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
David RoseCardiac Surgery, Lancashire Cardiac Centre, Blackpool Victoria Hospital, Blackpool, UK.
Francesco PiccirilloCardiology, Università Campus Bio-Medico di Roma, Rome, Italy.
Annunziata NuscaCardiology, Università Campus Bio-Medico di Roma, Rome, Italy.
Francesco GrigioniCardiology, Università Campus Bio-Medico di Roma, Rome, Italy.
Massimo ChelloCardiac Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
Gus J VlahakesCardiac Surgery, Massachusetts General Hospital & Harvard Medical School, Boston, USA.
Università Campus Bio-Medico · ITHarvard University · USUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgical myocardial revascularization is associated with long-term survival benefit in patients with multivessel coronary artery disease. However, the exact biological mechanisms underlying the clinical benefits of myocardial revascularization have not been elucidated yet. Angiogenesis and arteriogenesis biologically leading to vascular collateralization are considered one of the endogenous mechanisms to preserve myocardial viability during ischemia, and the presence of coronary collateralization has been regarded as one of the predictors of long-term survival in patients with coronary artery disease (CAD). Some experimental studies and indirect clinical evidence on chronic CAD confirmed an angiogenetic response induced by myocardial revascularization and suggested that revascularization procedures could constitute an angiogenetic trigger per se. In this review, the clinical and basic science evidence regarding arteriogenesis and angiogenesis in both CAD and coronary revascularization is analyzed with the aim to better elucidate their significance in the clinical arena and potential therapeutic use.

Indexed as

Coronary Artery DiseaseMyocardial InfarctionPercutaneous Coronary InterventionHumansMyocardial RevascularizationTreatment OutcomeAngiogenesisArteriogenesisCoronary artery bypass graftMyocardial infarctionMyocardial revascularizationPercutaneous coronary intervention

Identifiers

PMID35357670
OpenAlexW4220945493

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.