Evidence mapPaperPMID 35359802Full record

ReviewiScience2022

Mathematical models to study the biology of pathogens and the infectious diseases they cause.

Joao B Xavier, Jonathan M Monk, Saugat Poudel, Charles J Norsigian, Anand V Sastry, Chen Liao, Jose Bento, Marc A Suchard, Mario L Arrieta-Ortiz, Eliza J R Peterson and 10 more

Open access · goldAbstract readReview
In one paragraph

Review in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 1 country.

Joao B XavierProgram for Computational and Systems Biology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Jonathan M MonkDepartment of Bioengineering, UC San Diego, San Diego, CA, USA.
Saugat PoudelDepartment of Bioengineering, UC San Diego, San Diego, CA, USA.
Charles J NorsigianDepartment of Bioengineering, UC San Diego, San Diego, CA, USA.
Anand V SastryDepartment of Bioengineering, UC San Diego, San Diego, CA, USA.
Chen LiaoProgram for Computational and Systems Biology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Jose BentoComputer Science Department, Boston College, Chestnut Hill, MA, USA.
Marc A SuchardDepartment of Computational Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, USA.
Mario L Arrieta-OrtizInstitute for Systems Biology, Seattle, WA, USA.
Eliza J R PetersonInstitute for Systems Biology, Seattle, WA, USA.
Nitin S BaligaInstitute for Systems Biology, Seattle, WA, USA.
Thomas StoegerDepartment of Chemical and Biological Engineering; Northwestern University, Evanston, IL 60208, USA.
Felicia RuffinDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Reese A K RichardsonDepartment of Chemical and Biological Engineering; Northwestern University, Evanston, IL 60208, USA.
Catherine A GaoSuccessful Clinical Response in Pneumonia Therapy (SCRIPT) Systems Biology Center, Northwestern University, Chicago, IL, USA.
Thomas D HorvathDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Anthony M HaagDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Qinglong WuDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Tor SavidgeDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Michael R YeamanDavid Geffen School of Medicine at UCLA & Lundquist Institute for Infection & Immunity at Harbor UCLA Medical Center, Los Angeles, CA, USA.
Baylor College of Medicine · USUniversity of California San Diego · USInstitute for Systems Biology · USNorthwestern University · USMemorial Sloan Kettering Cancer Center · USBoston College · USDuke University · USUCLA Medical Center · USUniversity of California, Los Angeles · US

Funding

The Patient-Reported Outcomes, Community-Engagement and Language (PRO-CEL) CoreP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · 1985 to 2025
$88.4M
Technology CoreU19AI135964 · NIAID · NORTHWESTERN UNIVERSITY · 2022 to 2025
$20.7M
Technology CoreU19AI135995 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · 2023 to 2025
$13.9M
Technology CoreU19AI135976 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI ALAN A ADEREM · 2022 to 2022
$6.8M
NCI NIH HHS P30 CA008748NIAID NIH HHS U01 AI124275NIAID NIH HHS U01 AI124290NIAID NIH HHS U01 AI124302NIAID NIH HHS U01 AI124316NIAID NIH HHS U01 AI124319NIAID NIH HHS U19 AI135964NIAID NIH HHS U19 AI135976NIAID NIH HHS U19 AI135995
6 · The paper itself

Abstract

Mathematical models have many applications in infectious diseases: epidemiologists use them to forecast outbreaks and design containment strategies; systems biologists use them to study complex processes sustaining pathogens, from the metabolic networks empowering microbial cells to ecological networks in the microbiome that protects its host. Here, we (1) review important models relevant to infectious diseases, (2) draw parallels among models ranging widely in scale. We end by discussing a minimal set of information for a model to promote its use by others and to enable predictions that help us better fight pathogens and the diseases they cause.

Indexed as

Computer modelingInfection control in health technologyMicrobiology

Identifiers

PMID35359802
PMCPMC8961237
OpenAlexW4220943831

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.